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Experimental and Clinical Gastroenterology

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Thyroid status in children with chronic gastroduodenitis and related atopic diseases

Abstract

The aim was to investigate the thyroid status in children with chronic gastroduodenitis in combination with such atopic diseases as bronchial asthma and atopic dermatitis. Materials and мethods. 39 children of pre-pubertal age that have a morphologically confirmed diagnosis of chronic gastroduodenitis-CGD were examined with an ELISA. The children were divided into 2 groups: 1 - a group of 16 children with HGD only; the second is 23 children with CGD and atopy. Results. In both groups, the mean T3, T4, T4cb, TTG levels and the number of patients with normal levels of thyroid hormones in the blood serum were the same. A higher level of antibodies to thyroglobulin was found in patients with CGD and atopy and a higher level of antibodies to thyroid peroxidase in patients with CGD only. The mechanism of the revealed differences requires additional study.

About the Authors

A. P. Listopadova
Public budgetary educational institution of higher education “St. Petersburg State Pediatric Medical University ” of the Ministry of Healthcare of the Russia
Russian Federation


E. A. Zemskova
St.Petersburg public budgetary Health care institution “Children's Сity Policlinic № 8” of the Ministry of Healthcare of the Russia
Russian Federation


Yu. E. Zamyatina
Public budgetary educational institution of higher education “St. Petersburg State Pediatric Medical University ” of the Ministry of Healthcare of the Russia; St.Petersburg public budgetary Health care institution “Children's Сity Policlinic № 8” of the Ministry of Healthcare of the Russia
Russian Federation


L. V. Tyrtova
Public budgetary educational institution of higher education “St. Petersburg State Pediatric Medical University ” of the Ministry of Healthcare of the Russia
Russian Federation


O. P. Gurina
Public budgetary educational institution of higher education “St. Petersburg State Pediatric Medical University ” of the Ministry of Healthcare of the Russia
Russian Federation


A. E. Blinov
Public budgetary educational institution of higher education “St. Petersburg State Pediatric Medical University ” of the Ministry of Healthcare of the Russia
Russian Federation


O. N. Varlamova
Public budgetary educational institution of higher education “St. Petersburg State Pediatric Medical University ” of the Ministry of Healthcare of the Russia
Russian Federation


A. I. Khavkin
Pirogov Russian National Research Medical University of the Ministry of Health, Moscow, Russian Federation
Russian Federation


Review

For citations:


Listopadova A.P., Zemskova E.A., Zamyatina Yu.E., Tyrtova L.V., Gurina O.P., Blinov A.E., Varlamova O.N., Khavkin A.I. Thyroid status in children with chronic gastroduodenitis and related atopic diseases. Experimental and Clinical Gastroenterology. 2018;(7):151-154. (In Russ.)

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ISSN 1682-8658 (Print)