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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nogr-968</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Тиреоидный статус у детей с хроническим гастродуоденитом и сопутствующими атопическими заболеваниями</article-title><trans-title-group xml:lang="en"><trans-title>Thyroid status in children with chronic gastroduodenitis and related atopic diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Листопадова</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Listopadova</surname><given-names>A. P.</given-names></name></name-alternatives><email xlink:type="simple">A.listopadova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Земскова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zemskova</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Замятина</surname><given-names>Ю. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Zamyatina</surname><given-names>Yu. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тыртова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tyrtova</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гурина</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Gurina</surname><given-names>O. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блинов</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Blinov</surname><given-names>A. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Варламова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Varlamova</surname><given-names>O. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хавкин</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khavkin</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Минздрава России; СПб ГБУЗ «Детская городская поликлиника № 8», Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Public budgetary educational institution of higher education “St. Petersburg State Pediatric Medical University ” of the Ministry of Healthcare of the Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>СПб ГБУЗ «Детская городская поликлиника № 8», Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St.Petersburg public budgetary Health care institution “Children's Сity Policlinic № 8” of the Ministry of Healthcare of the Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Минздрава России; СПб ГБУЗ «Детская городская поликлиника № 8», Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Public budgetary educational institution of higher education “St. Petersburg State Pediatric Medical University ” of the Ministry of Healthcare of the Russia; St.Petersburg public budgetary Health care institution “Children's Сity Policlinic № 8” of the Ministry of Healthcare of the Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Public budgetary educational institution of higher education “St. Petersburg State Pediatric Medical University ” of the Ministry of Healthcare of the Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н. И. Пирогова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University of the Ministry of Health, Moscow, Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>20</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>7</issue><fpage>151</fpage><lpage>154</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Листопадова А.П., Земскова Е.А., Замятина Ю.Е., Тыртова Л.В., Гурина О.П., Блинов А.Е., Варламова О.Н., Хавкин А.И., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Листопадова А.П., Земскова Е.А., Замятина Ю.Е., Тыртова Л.В., Гурина О.П., Блинов А.Е., Варламова О.Н., Хавкин А.И.</copyright-holder><copyright-holder xml:lang="en">Listopadova A.P., Zemskova E.A., Zamyatina Y.E., Tyrtova L.V., Gurina O.P., Blinov A.E., Varlamova O.N., Khavkin A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/968">https://www.nogr.org/jour/article/view/968</self-uri><abstract><p>Цель исследования - оценить тиреоидный статус у детей с хроническим гастродуоденитом в сочетании такими атопическими заболеваниями, как бронхиальная астма и атопический дерматит. Материалы и методы: Обследовано методом ИФА 39 детей допубертатного возраста, имеющих имеющих морфологически подтвержденный диагноз «хронический гастродуоденит-ХГД». Дети были разделены на 2 группы: 1 - группа- 16 детей только с ХГД; вторая- 23 ребенка с ХГД и атопией. Результаты. В обеих группах средний уровень Т3, Т4, Т4св, ТТГ и число больных с нормальным уровнем тиреоидных гормонов в сыворотке крови были одинаковы. Выявлены более высокий уровень антител к тиреоглобулину у больных с ХГД и атопией и более высокий уровень антител к тиреоидной пероксидазе у больных только с ХГД. Механизм выявленных различий требует дополнительного изучения.</p></abstract><trans-abstract xml:lang="en"><p>The aim was to investigate the thyroid status in children with chronic gastroduodenitis in combination with such atopic diseases as bronchial asthma and atopic dermatitis. Materials and мethods. 39 children of pre-pubertal age that have a morphologically confirmed diagnosis of chronic gastroduodenitis-CGD were examined with an ELISA. The children were divided into 2 groups: 1 - a group of 16 children with HGD only; the second is 23 children with CGD and atopy. Results. In both groups, the mean T3, T4, T4cb, TTG levels and the number of patients with normal levels of thyroid hormones in the blood serum were the same. A higher level of antibodies to thyroglobulin was found in patients with CGD and atopy and a higher level of antibodies to thyroid peroxidase in patients with CGD only. The mechanism of the revealed differences requires additional study.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>антител к тиреоидной пероксидазе</kwd><kwd>антитела к тиреоглобулину</kwd><kwd>тиреоидный статус</kwd><kwd>атопия</kwd><kwd>дети</kwd><kwd>гастродуоденит</kwd><kwd>thyroid peroxidase antibodies</kwd><kwd>thyroglobulin antibodies</kwd><kwd>thyroid status</kwd><kwd>atopy</kwd><kwd>children</kwd><kwd>gastroduodenitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
