Systematic analysis of lactitol studies
          
      
    
      
    
                        
              https://doi.org/10.31146/1682-8658-ecg-162-2-131-142
        
          
    
  
      
  
    
                
            Abstract
            Lactitol is a prebiotic disaccharide that supports the functioning of lacto- and bifidobacteria, also inhibits the growth of pathogenic flora. The results of transcriptome and proteomic studies have shown that lactitol is characterized by unique absorption and processing mechanisms in lactobacteriathat distinguish it from other prebiotics. In high doses (5 … 50 g/day) lactiol is used as an osmotic laxative. Lactictol enhances the detoxification of the body (in particular, the excretion of ammonia and toxic amines). The detoxification effect of lactitol, lack of lactitol’seffect on blood lipid and glycemic profiles, lack of food intolerance and rare occurrenceof side effects (flatulence, transient diarrhea when the dose is exceeded) make lactitol an important tool in the treatment of dysbiosis, liver disease and hepatic encephalopathy.
         
              
        
                        		
                     
    
      
                  About the Authors
              
               
             O. A. Gromova
         
        
                        Big Data Storage and Analysis Center (CCHD), Moscow State University
        
Russian Federation
    
				    
    
    
             
             I. Yu. Torshin
         
        
                        Big Data Storage and Analysis Center (CCHD), Moscow State University
        
Russian Federation
    
				    
    
    
             
             V. A. Maximov
         
        
                        Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuous Professional Education” of the Ministry of Healthcare of the Russian Federation
        
Russian Federation
    
				    
    
    
             
             A. N. Gromov
         
        
                        Big Data Storage and Analysis Center (CCHD), Moscow State University
        
Russian Federation
    
				    
    
    
             
             K. V. Rudakov
         
        
                        Big Data Storage and Analysis Center (CCHD), Moscow State University
        
Russian Federation
    
				    
    
    
          
     
        
    
    
    
 
    
 
  
    
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