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Experimental and Clinical Gastroenterology

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Systematic analysis of lactitol studies

https://doi.org/10.31146/1682-8658-ecg-162-2-131-142

Abstract

Lactitol is a prebiotic disaccharide that supports the functioning of lacto- and bifidobacteria, also inhibits the growth of pathogenic flora. The results of transcriptome and proteomic studies have shown that lactitol is characterized by unique absorption and processing mechanisms in lactobacteriathat distinguish it from other prebiotics. In high doses (5 … 50 g/day) lactiol is used as an osmotic laxative. Lactictol enhances the detoxification of the body (in particular, the excretion of ammonia and toxic amines). The detoxification effect of lactitol, lack of lactitol’seffect on blood lipid and glycemic profiles, lack of food intolerance and rare occurrenceof side effects (flatulence, transient diarrhea when the dose is exceeded) make lactitol an important tool in the treatment of dysbiosis, liver disease and hepatic encephalopathy.

For citations:


Gromova O.A., Torshin I.Yu., Maximov V.A., Gromov A.N., Rudakov K.V. Systematic analysis of lactitol studies. Experimental and Clinical Gastroenterology. 2019;(2):131-142. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-162-2-131-142

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ISSN 1682-8658 (Print)