CHANGES OF THE MUCOUS MEMBRANE OF THE ORAL CAVITY IN THE CHRONIC EROSIVE GASTRITIS ASSOCIATED WITH HELICOBACTER PYLORI AND HERPES INFECTION
Abstract
Aim. In the article frequency of defeat of mucous membranes of organs of cavity of mouth and tissues of paradontium is examined at intensifying of chronic erosive gastritis associated with Helicobacter pylori and herpes viral infection. Result. As a result of the study in patients suffering from chronic erosive gastritis associated with Helicobacter pylori and herpesvirus infection, Helicobacter pylori was detected in 100% of cases in the gastric mucosa in the study of biopsies by PCR, urease test, microscopy of smears and in the oral cavity in the study by urease test and PCR method, while the degree of contamination was regarded as high and medium. All patients were divided into 2 groups depending on the severity of the disease. Significantly more often in the first group of studies compared with the second identified high and very high rate of the CPU (χ2=14,280 at p<0.01); the index of hygiene is very poor and unsatisfactory (χ2=11,752; χ2=11,509, at p<0.01, respectively); gingivitis severe (χ2=20,847 when p<0.01); severe inflammation of the gums (χ2=14,849, p<0.01); the third stage of periodontal disease (χ2=26,615 at p<0.05) in the assessment of dental status. No periodontitis was observed in the control group. Conclusions. The infection of Helicobacter pylori serves as the base-line factor of forming of inflammatory diseases of paradontium, initiating development of active erosive gastritis, nosotropic closely associated with gingivitis and periodontitis.
About the Authors
T. E. Afanasenkova
Smolensk state medical University
Russian Federation
Russian Federation
E. E. Dubskaya
Smolensk state medical University
Russian Federation
Russian Federation
L. I. Devlikanova
Smolensk state medical University
Russian Federation
Russian Federation
References
1. Цимбалистов А.В., Робакидзе НС. Патофизиологические аспекты развития сочетанной патологии полости рта и желудочно-кишечного тракта, Стоматология для всех, 2005, 1, 28-34
2. Валенкевич Л.Н., Яхонтова О. И. Болезни органов пищеварения. Руководство по гастроэнтерологии для врачей. - СПб.: Изд-во ДЕАН, 2006, 656 с
3. Рапопорт С. И. Гастриты. Пособие для врачей. Москва, 2010, 20 с
4. Циммерман Я. С. Этиология, патогенез и лечение язвенной болезни, ассоциированной с Helicobacter pylori-инфекцией: состояние проблемы и перспективы, Клиническая медицина, 2006, № 3, С. 1-7
5. Al-Hawajri A.A., Keret D., Simhon A. et al. Helicobacter pylori DNA in dental plaques, gastroscopy, and dental devices, Digestion disease science, 2004, Vol. 49, № 7/8, P. 1091-1094.
6. humpitaz C.J., Gutierraz M. J., Cordova A. R. et al. isolation of helicobacter pylori in dental plaque in patients with gastritis at «Angamos» clinic, Review gastroenterology Peru, 2006, Vol. 26, № 4, P. 373-376.
7. Honda K., Ohrusa T., Takashimuzu I. et al. High risk of Helicobacter pylori infection in young Japanese dentists, Journal of gastroenterology and hepatology, 2001, Vol. 16, № 8, P. 862-865.
8. Chisazi M.t., Fattahi E., Farahani R. M. et al. Helicobacter pylori in the dental plaque: is it of diagnostics value for gastric infection? Medical oral pathology and oral cirbucalis, 2006, Vol. 11, № 4, P. 325-328.
9. Czesnikiewicz-Guzik M., Bielanski W., Guzikt.J. et al. Helicobacter pylori in the oral cavity and its implications for gastric infection, periodontal health, immunology and dyspepsia, Journal of physiology and pharmacology, 2005, Vol. 56. (Suppl 6), P. 77-89.
10. Nasrolahei M., Malekii., Emadian O. Helicobacter pylori colonization in dental plaque and gastric infection, Rom journal of gastroenterology, 2003, Vol. 12, № 4, P. 293-296.
11. Ogunbodede E.O., Lawal O. O., Lamikanra A. et al. Helicobacter pylori in the dental plaque and gastric mucosa of dyspeptic Nigerian patients, tropical gastroenterology, 2002, Vol. 23, № 3, P. 127-133.
12. Umeda M., Kobayashi Y., Takeuchi Y et al. High prevalence of Helicobacter pylori detected by PCR in the jral cavities of periodontitis patients, Journal of periodontology, 2003, Vol. 74, № 1, P. 129-134
13. Базикян Э.А., Маев И. В., Николаева Е. Н. и др. Сравнение инвазивных и неинвазивных методов выявления Helicobacter pylori в желудке и полости рта у больных с кислотозависимыми заболеваниями. РЖГГК. 2008. № 4. С. 32-37.
14. Нейзберг Д.М., Стюф И. Ю. Роль эктопических очагов Helicobacter pylori при хроническом генерализованом пародонтите. Пародонтология № 2 (59),2011. С. 9-13
15. Цимбалистов А.В., Робакидзе Н. С. Влияние стоматологического статуса больных язвенной болезнью на инфицированность полости рта и слизистой оболочки желудка Helicobacter pylori. Клин. Стоматология, 2000, № 3, С. 16-18
16. Gebara E.C., Faria C. M., Pannuti C. et al. Persistence of Helicobacter pylori in the oral cavity after systemic eradication therapy, J. Clin. Periodontol, 2006, Vol. 33, N5, P. 329-333
17. Ozdemir A., Mas M. R., Sahin S. et al. Department of Periodontology, Gеlhane Military Medical Academy, QuintessenceInt, 2001, Vol. 32, N2, P. 131-134
18. Anand P.S., Nandakumar К., Shenoy К. Т. Are dental plaque, poor oral hygiene, and periodontal disease associated with Helicobacter pylori infection? JPeriodontal, 2006, 77, 4, 692-698
19. Аруин Л. И. Helicobacter pylori: каким образом один возбудитель вызывает разные болезни. Экспериментальная и клиническая гастроэнтерология 2004; 1: 36-41
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For citations:
Afanasenkova T.E., Dubskaya E.E., Devlikanova L.I. CHANGES OF THE MUCOUS MEMBRANE OF THE ORAL CAVITY IN THE CHRONIC EROSIVE GASTRITIS ASSOCIATED WITH HELICOBACTER PYLORI AND HERPES INFECTION. Experimental and Clinical Gastroenterology. 2018;(6):16-21. (In Russ.)
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