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Experimental and Clinical Gastroenterology

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FEATURES DIAGNOSIS AND TREATMENT OF CANDIDIASIS OF THE UPPER DIGESTIVE TRACT IN PATIENTS WITH METABOLIC SYNDROME

Abstract

The article presents modern principles of diagnostics and treatment of candidiasis of the upper digestive tract (oropharynx and esophagus) described the clinical picture and complications of this disease. Metabolic syndrome, occurring with disorders of carbohydrate metabolism - a typical risk factor for candidiasis. Standard for diagnosis is the detection of filamentous forms (pseudomycelium) of micromycetes of the genus Candida a morphological study of biomaterials mucous membrane. Culture of biopsy specimens with identification of the species of the pathogen becomes mandatory for maintaining tolerance to standard treatment or recurrent candidiasis. The drug of choice when treating candidiasis is fluconazole, however, in some cases, necessary alternative antimycotic drugs. Feature of the treatment of candidiasis in patients with the metabolic syndrome is an increased risk of drug damage to the cookies, especially against the background of steatosis and steatohepatitis, which is characteristic for this category of patients.

About the Authors

M. A. Shevyakov
North-Western State Medical University named after I. I. Mechnikov
Russian Federation


Yu. P. Uspenskiy
Saint-Petersburg State Pediatric Medical University
Russian Federation


References

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Review

For citations:


Shevyakov M.A., Uspenskiy Yu.P. FEATURES DIAGNOSIS AND TREATMENT OF CANDIDIASIS OF THE UPPER DIGESTIVE TRACT IN PATIENTS WITH METABOLIC SYNDROME. Experimental and Clinical Gastroenterology. 2017;(7):161-166. (In Russ.)

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ISSN 1682-8658 (Print)