ARTERIAL STIFF NESS IN METABOLIC SYNDROME AND GENERALIZED PERIODONTITIS
Abstract
The purpose of the review. To highlight the state of arterial stiffness problem of the metabolic syndrome and generalized periodontitis with clinical, laboratory and instrumental and morphological and functional positions. Recent data on the problem indicate the conjugation of the metabolic syndrome and generalized periodontitis with characteristic changes in arterial stiffness. It is assumed, on the one hand, a fundamental role of generalized periodontitis in the development of immunological processes in the body with the development of atherosclerotic cardiovascular diseases including metabolic disorders with the formation of the insulin resistance syndrome and on the other hand, indicates that hyperinsulinemia, hyperglycemia, dyslipidemia and microcirculatory disturbances increase arterial stiffness. According to the authors, the trigger generalized periodontitis progression of the metabolic syndrome, inflammation appears closely paired with an increase in arterial stiffness. Conclusion. Changes in generalized periodontitis, including vascular stiffness characteristic of the metabolic syndrome, secondary, not only on the background, but also contribute to the progression of the syndrome and the development of complications, closing circle of pathogenesis.
About the Authors
A. I. Sabirova
Kyrgyz-Russian Slavic University named after B. N. Yeltsin
Russian Federation
Russian Federation
A. B. Mamytova
Kyrgyz-Russian Slavic University named after B. N. Yeltsin
Russian Federation
Russian Federation
I. S. Sabirov
Kyrgyz-Russian Slavic University named after B. N. Yeltsin
Russian Federation
Russian Federation
I. T. Murkamilov
Kyrgyzstan State Medicine Academy named after I. K. Akhunbaev
Russian Federation
Russian Federation
References
1. Kornman KS. Mapping the pathogenesis of periodontitis: A new look. // J Periodontol.-2008. -Vol. 79(Suppl. 8). - P. 1560-1568.
2. Azarpazhooh A., Tenenbaum H. C. Periodontitis: a syndromic condition. // J Can Dent Assoc. - 2012. - Vol.78. - P.27.
3. Грудянов А. И., Овчинникова В. В. Воспалительные заболевания пародонта как фактор риска развития патологии сердечно-сосудистой системы (обзор литературы) // Стоматология. - 2007. - № 5. - С. 76-78.
4. Blaizot A, Vergnes JN, Nuwwareh S et al. Periodontal diseases and cardiovascular events: Meta-analysis of observational studies. // Int Dent J. - 2009. -Vol.59. - P. 197-209.
5. Карпенко И. Н., Булкина Н. В., Понукалина Е. В. Современные представления об этиологии и патогенезе быстропрогрессирующего пародонтита // Архив патологии. - 2009. - № 1. - С. 57-59.
6. Subramanian S, Emami H, Vucic E et al. High Dose Atorvastatin Reduces Periodontal Inflammation: A Novel Pleiotropic Effect of Statins. // J Am Coll Cardiol. - 2013 Dec 24. -Vol. 62(25). - P. 2382-91.
7. Vincent E. Friedewald, Kenneth S. Kornman, James D. Beck et al. The American Journal of Cardiology and Journal of Periodontology Editors’ Consensus: Periodontitis and Atherosclerotic Cardiovascular Diseaser. // J Periodontol. - July 2009. - P. 1021-1032.
8. John Beilby. Definition of Metabolic Syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition. // Clin Biochem Rev. - 2004 Aug. - Vol; 25(3). - P. 195-198.
9. Кондаков И. К., Коваль С. Н., Снегурская И. А. К проблеме патогенеза метаболического синдрома. Жировая ткань и маркеры острой фазы воспаления // Артериальная гипертензия. - 2009. - № 3 (5). - С. 39-42.
10. Graham I, Atar D, Borch-Johnsen K et al. European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts). // Eur J Cardiovasc Prev Rehabil. - 2007. - Vol. 14 (Suppl 2). - S 1-S 113.
11. Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. // J Am Coll Cardiol. - 2010. - Vol. 55(13). - P. 1318-1327.
12. Кочкина М. С., Евдокимова М. А., Асейчева О. Ю. и соавторы. Скорость распространения пульсовой волны и риск развития фатальных исходов у больных с артериальной гипертензией, перенесших обострение ишемической болезни сердца. // Кардиология. - 2012. - № 2. - С. 4-11.
13. Драпкина О. М., Дадаева В. А. Хроническая сердечная недостаточность начинается с периферии? Жесткие сосуды, жесткий миокард. // Российские медицинские вести. - 2014. - Том XIX, № 1. - С. 61-65.
14. Кочкина М. С. Затейщиков Д. А., Сидоренко Б. А. Измерение жесткости артерий и ее клиническое значение. // Кардиология. - 2005. -№ 1. - С. 63-71.
15. Максимов Н. И., Ополонский Д. В. Структурные и функциональные изменения артериальных сосудов у больных ишемической болезнью сердца с метаболическим синдромом. // Кардиология. - 2009. - № 6. - С. 10-14.
16. Викентьев В. В., Сметнева Н. С., Самохина Д. Г. Структурные и функциональные особенности артерий при ультразвуковом исследовании у больных с эндотелиальной дисфункцией, страдающих метаболическим синдромом. // Вестник РУДН, серия Медицина. - 2008. - № 8. - C. 288-292.
17. Avolio A. P. Pulse wave velocity and hypertension // Arterial and venous systems in essential hypertension / ed. M. Safar. - Boston, Mass: Martinus Nijhoff. - 1991. - Р. 133-152.
18. Jung YS, Shin MH, Kim IS et al. Relationship between periodontal disease and subclinical atherosclerosis: the Dong-gu Study. // J Clin Periodontol. -2013. - Vol. 41. - P. 262-268.
19. Orlandi M, Suvan J, Petrie A. et al. Association between periodontal disease and its treatment, flow-mediated dilatation and carotid intima-media thickness: a systematic review and meta-analysis. // Atherosclerosis. - 2014 Sep. - Vol. 236(1). - P. 39-46.
20. Vlachopous C., Dima I., Aznaouridis K. et al. Acute systemic inflammation icreases arterial stiffness and decreases wave reflections in healthy individuals. // Circulation. - 2005. - Vol.112. - P. 2193-2200.
21. Schillaci G., Pirro M., Vaudo G. et al. Metabolic syndrome is associated with aortic stiffness in untreated essential hypertension // Hypertension. - 2005. - № 45. - Р. 1078-1082.
22. Ребров А. П., Никитина Н. М., Кароли Н. А. и соавторы. Жесткость артерий в зависимости от наличия факторов риска развития сердечно-сосудистых заболеваний // Терапевтический архив. - 2009. - № 3. - С. 54-57.
23. Гударьян А. А. Частота и особенности клинического проявления генерализованного пародонтита при различных компонентах метаболического синдрома // Вестник стоматологии. - 2003. - № 1. - С. 20-25.
24. Nakanishi N., Shiraishi T., Wada M. Brachial-ankle pulse wave velocity and metabolic syndrome in a Japanese population: the Minoh study // Hypertens Res. - 2005. - № 28 (2). - P. 125-31.
25. Tomiyama H., Коji Y., Yambe M. et al. Elevated C-reactive protein augments increased arterial stiffness in subjects with the metabolic syndrome // Hypertension. - 2005. - № 45 (5). - Р. 997-1003.
26. Дружилов М. А., Дружилова О. Ю., Отмахов В. В. и соавторы. Значение оценки артериальной жесткости при метаболическом синдроме. // Российский кардиологический журнал. - 2015. - № 12. - P. 45-49.
27. Choi K. M., Lee K. W., Seo J. A. et al. Relationship between brachial-ankle pulse wave velocity and cardiovascular risk factors of the metabolic syndrome. // Diabetes Res Clin Pract. - 2004. - Oct. 66 (1). - Р. 57-61.
28. Sutton-Tyrrell K., Newman A., Havlik R. еt al. Aortic stiffness is associated with visceral adiposity in older adults ehrolled in the study of health, aging, and body composition // Hypertension. - 2001. - № 38. - Р. 429.
29. Sengstock D. M., Vaitkevicius P. V., Supiano M. A. Arterial stiffeness is related to insulin resistance in nondiabetic hypertensive older adults // The J. of Clin Endocrinology and metabolism. - 2004. - Vol. 90 (5). - Р. 2823-2827.
30. Ройберг Г. Е. - Метаболический синдром / под ред. Г. Е. Ройберга. - М.: МЕДпрессинформ, 2007. - 224 с.
31. Day K. Metabolic syndrome, or what jou will: definitions and epidemiology // Diab. Vasc. Dis. Res. - 2007. - Vol. 4, № 1. - Р. 32-38
32. Чазова И. Е., В. Б. Мычка. Метаболический синдром. - М.: Медиа Медика. - 2004. - 113 с.
33. Соколов, Е. И. Диабетическое сердце. - М.: Медицина, 2002. - 267 с.
34. Vyssoulis G. P., Pietri P. G., Karpanou E. A. Differential impact of metabolic syndrome on arterial stiffness and wave refl ections: Focus on distinct definitions // Int. J. Cardiol. - 2010. - Vol. 138(2). - P. 119-125.
35. Saba P. S., Roman M. J., Longhini C. et al. Carotid intimal-medial thickness and stiffness are not affected by hypercholesterolemia in uncomplicated essential hypertension // Arterioscler. Thromb. Vasc. Biol. - 1999. - Vol. 19. - № 11. - P. 2788-2794.
36. Aznaouridis K., Vlachopoulos C., Dima I. Triglyceride level is associated with wave reflections and arterial stiffness in apparently healthy middle-aged men // Heart. - 2007. - Vol. 93, № 5. - P. 613-614.
37. Miyaki K, Masaki K, Naito M et al. Periodontal disease and atherosclerosis from the viewpoint of the relationship between community periodontal index of treatment needs and brachial-ankle pulse wave velocity. // BMC Public Health. - 2006. - Vol. 6. - P. 131.
38. Franek E, Blaschyk R, Kolonko A et al. Chronic periodontitis in hemodialysis patients with chronic kidney disease is associated with elevated serum C-reactive protein concentration and greater intima-media thickness of the carotid artery. // J Nephrol. - 2006. - Vol.19(3). - P. 346-351.
39. Vieira CL, Cury PR, Miname MH et al. Severe periodontitis is associated with diastolic blood pressure elevation in individuals with heterozygous familial hypercholesterolemia: a pilot study. // J Periodontol. - 2011. - Vol. 82(5). - P. 683-688.
40. Vidal F, Cordovil I, Figueredo CM, Fischer RG. Non-surgical periodontal treatment reduces cardiovascular risk in refractory hypertensive patients: a pilot study. // J Clin Periodontol. - 2013. - Vol.40(7). - P. 681-687.
41. Трухан Д. И., Викторова И. В. Изменение органов и тканей полости рта при заболеваниях внутренних органов. / - М.: Практическая медицина, 2012. - 208 с.
42. Hanaoka Y, Soejima H, Yasuda O et al. Level of serum antibody against a periodontal pathogen is associated with atherosclerosis and hypertension. // Hypertens Res. - 2013. -Vol. 36(9). - P. 829-833.
43. Jockel-Schneider Y, Harks I, Haubitz I et al. Arterial stiffness and pulse wave reflection are increased in patients suffering from severe periodontitis. // PloS one. - 2014. - Vol. 9(8). - e103449.
44. Kapellas K, Jamieson LM, Do LG et al. Associations between periodontal disease and cardiovascular surrogate measures among Indigenous Australians. // Int J Cardiol. - 2014. - Vol. 173(2). - P. 190-196.
45. Shanker J, Setty P, Arvind P et al. Relationship between periodontal disease, Porphyromonas gingivalis, peripheral vascular resistance markers and coronary artery disease in Asian Indians. // Thromb Res. - 2013. - Vol. 132(1). - P. 8-14.
46. Teeuw WJ, Slot DE, Susanto H et al. Treatment of periodontitis improves the atherosclerotic profile: a systematic review and meta-analysis. // J Clin Periodontol. - 2014. - Vol. 41(1). - P. 70-79.
47. Seinost G, Wimmer G, Skerget M et al. Periodontal treatment improves endothelial dysfunction in patients with severe periodontitis. // Am Heart J. - 2005. - Vol.149(6). - P. 1050-1054.
48. Piconi S, Trabattoni D, Luraghi C et al. Treatment of periodontal disease results in improvements in endothelial dysfunction and reduction of the carotid intima-media thickness. // FASEB J. - 2009. - Vol. 23(4). - P. 1196-1204.
49. W Houcken, W J Teeuw, S Bizzarro et al. Arterial stiffness in periodontitis patients and controls. // Human Hypertension. -2015. -Vol.30. - P. 24-29.
50. Kapellas K, Maple-Brown LJ, Jamieson LM et al. Effect of periodontal therapy on arterial structure and function among aboriginal Australians: a randomized, controlled trial. // Hypertension. - 2014. - Vol. 64(4). - P. 702-708.
Review
For citations:
Sabirova A.I., Mamytova A.B., Sabirov I.S., Murkamilov I.T. ARTERIAL STIFF NESS IN METABOLIC SYNDROME AND GENERALIZED PERIODONTITIS. Experimental and Clinical Gastroenterology. 2017;(6):99-104. (In Russ.)
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