Preview

Experimental and Clinical Gastroenterology

Advanced search

Functional constipation in children and adolescents: diagnostic and therapeutic algorithms

https://doi.org/10.31146/1682-8658-ecg-238-6-106-117

Abstract

The gastrointestinal pathology traditionally occupies a significant place in the structure of referrals to specialists such as family doctors and pediatricians, approximately 1/3 of referrals are related to constipation, of which 90% are functional. The symptoms of constipation in children are diverse and can, on the one hand, be manifested only by bowel movements, and on the other hand, include a complex of intestinal and extra-intestinal manifestations. The severity and features of the clinical manifestations of functional constipation may vary depending on the age of the child at the initial manifestation of symptoms, the characteristics of his nervous system, the state of intestinal motility, the duration of the disease, the anatomical features of the colon, the nature of the therapy used, the form and degree of compensation for constipation. The article presents data on the prevalence of pathology in childhood, a description of clinical symptoms, diagnostic criteria, features of interaction with the family of a child suffering from constipation, options for medication and non-drug treatment.

About the Authors

I. Yu. Melnikova
North-Western State Medical University named after I.I. Mechnikov
Russian Federation


E. G. Shapovalov
North-Western State Medical University named after I.I. Mechnikov
Russian Federation


References

1. Khavkin A.I., Fayzullina R.A., Belmer S.V. et al. Diagnosis and treatment of functional constipation in children (fragment of the Draft clinical guidelines for the diagnosis and treatment of functional diseases of the digestive system in children developed by the Russian Society of Pediatric Gastroenterologists, Hepatologists and Nutritionists). Farmateka. 2020;27(2):60-68. (in Russ.) doi: 10.18565/pharmateca.2020.2.60-68.

2. Constipation in Children: A Guide / I. Yu. Melnikova, V.P. Novikova, N.B. Dumova. - 3rd ed., revised and enlarged. - Moscow: GEOTAR-Media, 2020. - 160 p.: ill. - (Series “Library of a Specialist Physician”). (in Russ.) doi: 10.33029/9704-5783-2-СС3-2020-1-160.@@ Запоры у детей: руководство / И.Ю. Мельникова, В.П. Новикова, Н.Б. Думова. - 3-е изд., перераб. и доп. - Москва: ГЭОТАР-Медиа, 2020. - 160 с.: ил. - (Серия «Библиотека врача-специалиста»). doi: 10.33029/9704-5783-2-СС3-2020-1-160.

3. Belmer S.V., Khavkin A.I., Pechkurov D.V. Functional disorders of the digestive organs in children. Principles of diagnosis and treatment (in light of the Rome IV criteria). Series: Library of a specialist physician. Moscow: GEOTAR-Media, 2018. 180 p. (in Russ.)@@ Бельмер С.В., Хавкин А.И., Печкуров Д.В. Функциональные нарушения органов пищеварения у детей. Принципы диагностики и лечения (в свете Римских критериев IV). Серия: Библиотека врача-специалиста. М.: ГЭОТАР-Медиа, 2018. 180 с.

4. Rajindrajith S., Devanarayana N.M., Thapar N., Benninga M.A. Functional Fecal Incontinence in Children: Epidemiology, Pathophysiology, Evaluation, and Management. J Pediatr Gastroenterol Nutr. 2021;72:794-801. doi: 10.1097/MPG.0000000000003056.

5. Russo M., Strisciuglio C., Scarpato E., Bruzzese D., Casertano M., Staiano A. Functional Chronic Constipation: Rome III Criteria Versus Rome IV Criteria. J Neurogastroenterol Motil. 2019;25:123-128. doi: 10.5056/jnm18035.

6. Lewis S.J., Heaton K.W. Stool form scale as a useful guide to intestinal transit time. Scand J Gastroenterol. 1997;32:920-4. doi: 10.3109/00365529709011203

7. Vandenplas Y., Levy E., Lemmens R., Devreker T. Functional constipation in children. Pediatrics (Suppl. to the journal Consilium Medicum). 2017; 1: 50-57. (in Russ.)

8. Vandenplas Y., Levy E., Lemmens R., Devreker T. Функциональный запор у детей. Педиатрия (Прил. к журн. Consilium Medicum). 2017; 1: 50-57.

9. Zakharova I.N., Kulikov A.G., Osmanov I.M. et al. Functional constipation in children: modern diagnostic criteria and approaches to treatment. Pediatrics (Suppl. Consilium Medicum). 2018; 2: 51-57. (in Russ.) doi: 10.26442/2413-8460_2018.2.51-57.@@ Захарова И.Н., Куликов А.Г., Османов И.М. и др. Функциональный запор у детей: современные критерии диагностики и подходы к лечению. Педиатрия (Прил. к журн. Consilium Medicum). 2018; 2: 51-57. doi: 10.26442/2413-8460_2018.2.51-57.

10. Intestinal diseases in children: in 2 volumes / edited by S.V. Belmer, A. Yu. Razumovsky, A.I. Khavkin. Moscow. ID «MEDPRAKTIKA-M»; 2018. V. 2. 496 p. (in Russ.)@@ Болезни кишечника у детей: в 2 т. / под общ. ред. С.В. Бельмера, А.Ю. Разумовского, А.И. Хавкина. - М.: ИД «МЕДПРАКТИКА-М»; 2018. - Т. 2. - 496 с.

11. Constipation in children and young people: diagnosis and management. London: National Institute for Health and Care Excellence (NICE); 2017 Jul. (NICE Clinical Guidelines, No. 99.) Available from: https://www.ncbi.nlm.nih.gov/books/NBK554924/

12. Vriesman M.H., Benninga M.A. Functional constipation and fecal incontinence. In: Wyllie R. Pediatric gastrointestinal and liver diseases. Philadelphia: Elsevier, 2021: 106-118.

13. Belmer S.V., Volynets G.V., Gorelov A.V. et al. Functional digestive disorders in children. Guidelines of Society of Pediatric Gastroenterologists, Hepatologists and Nutritionists. Part 1. Ros Vestn Perinatol i Pediatr. 2020; 65:(4): 150-161 (in Russ.) doi: 10.21508/1027-4065-2020-65-4-150-161.@@ Бельмер С.В., Волынец Г.В., Горелов А.В., и др. Функциональные расстройства органов пищеварения у детей. Рекомендации Общества детских гастроэнтерологов, гепатологов и нутрициологов. Часть 3. Российский вестник перинатологии и педиатрии. 2020;65(6):133-144. doi: 10.21508/1027-4065-2020-65-4-150-161.

14. Suleymanova Z.Y., Ustinova N.V., Turti T.V. Features of Gastrointestinal Malformations in Children with Autism Spectrum Disorders: Literature Review. Pediatric pharmacology. 2022;19(2):99-104. (In Russ.) doi: 10.15690/pf.v19i2.2397.@@ Сулейманова З.Я., Устинова Н.В., Турти Т.В. Особенности гастроинтестинальных нарушений у детей с расстройствами аутистического спектра: обзор литературы. Педиатрическая фармакология. 2022;19(2):99-104. doi: 10.15690/pf.v19i2.2397

15. Hyams J.S., Di Lorenzo C., Saps M. et al. Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology. 2016;150:1456-68.

16. Melnikova I.Yu., Buryak V.N., Shapovalov E.G. Possibilities of increasing the effectiveness of therapy for functional disorders of the digestive system. / Proceedings of the annual (72nd) scientific and practical conference “New Horizons in Medical Science, Education and Practice” with international participation, dedicated to the 85th anniversary of the State Educational Institution “TSMU named after Abu Ali ibn Sino”, Vol. 1, 416 P. (in Russ.)@@ Мельникова И.Ю., Буряк В.Н., Шаповалов Е.Г. Возможности повышения эффективности терапии функциональных расстройств пищеварительной системы. /Материалы годичной (72-ой) научно-практической конференции «Новые горизонты в медицинской науке, образовании и практике» с международным участием, посвященной 85-летию ГОУ «ТГМУ им. Абуали ибни Сино», Т. 1, С. 416.

17. Rial R., Uc A. Functional constipation. In: Kleinman RE, Goulet O-J, Mieli-Vergani G, Sanderson IR, Sherman PM, Shneider BL, editors. Walker’s peadiatric gastrointestinal disease. United States: People’s medical publishing house. 2018: 991-1005.

18. Kamalova A.A., Shakirova A.R. Functional constipation in infants: Diagnosis and therapy in practice. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics). 2016;61(4):108-113. (In Russ.) doi: 10.21508/1027-4065-2016-61-4-108-113.@@ Камалова А.А., Шакирова А.Р. Функциональные запоры у детей раннего возраста: диагностика и терапия на практике. Российский вестник перинатологии и педиатрии. 2016;61(4):108-113. doi: 10.21508/1027-4065-2016-61-4-108-113.

19. Tran D.L., Sintusek P. Functional constipation in children: What physicians should know. World J Gastroenterol. 2023; 29(8): 1261-1288. doi: 10.3748/wjg.v29.i8.1261.

20. Ferreira-Maia A.P., Matijasevich A., Wang Y.P. Epidemiology of functional gastrointestinal disorders in infants and toddlers: A systematic review. World J Gastroenterol. 2016 Jul 28;22(28):6547-58. doi: 10.3748/wjg.v22.i28.6547.

21. Khavkin A.I., Fayzullina R.A., Belmer S.V. et al. Diagnostics and management tactics for children with functional constipation. Recommendations of the Society of Pediatric Gastroenterologists. Issues of Practical Pediatrics. 2014;9(5):62-76. (in Russ.)@@ Хавкин А.И., Файзуллина Р.А., Бельмер С.В. и др. Диагностика и тактика ведения детей с функциональными запорами. Рекомендации общества детских гастроэнтерологов. Вопросы практической педиатрии. 2014;9(5):62-76.

22. Allen P., Setya A., Lawrence V.N. Pediatric Functional Constipation. [Updated 2024 Jan 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537037/

23. Liu Z., Gang L., Yunwei M., Lin L. Clinical Efficacy of Infantile Massage in the Treatment of Infant Functional Constipation: A Meta-Analysis. Front Public Health. 2021;9:663581. doi: 10.3389/fpubh.2021.663581.

24. Vandenplas Y. et al. Functional gastro-intestinal disorder algorithms focus on early recognition, parental reassurance and nutritional strategies. Acta Paediatrica. 2016;105(3):244-25210.

25. Leung A.K., Hon K.L. Paediatrics: how to manage functional constipation. Drugs Context. 2021;10 doi: 10.7573/dic.2020-11-2.

26. Mulhem E., Khondoker F., Kandiah S. Constipation in Children and Adolescents: Evaluation and Treatment. Am Fam Physician. 2022 May 1;105(5):469-478. PMID: 35559625.


Review

For citations:


Melnikova I.Yu., Shapovalov E.G. Functional constipation in children and adolescents: diagnostic and therapeutic algorithms. Experimental and Clinical Gastroenterology. 2025;(6):106-117. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-238-6-106-117

Views: 9

JATS XML


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1682-8658 (Print)