The use of ursodeoxycholic acid preparations in the curation of patients in postcholecystectomy period: data from own observation
https://doi.org/10.31146/1682-8658-ecg-234-2-46-51
Abstract
The aim of our study was to evaluate the efficacy and safety of taking a universal hepatoprotector based on ursodeoxycholic acid in patients with cholelithiasis who underwent cholecystectomy. Materials and methods. The study involved 52 patients with cholelithiasis and changes in the lipid spectrum who underwent elective laparoscopic cholecystectomy. The patients were divided into 2 groups of 26 people, the first group received treatment with ursodeoxycholic acid after surgical treatment, the second group received only non-drug recommendations. All patients before the operation and 3 months after it underwent a biochemical blood test, lipidogram, ultrasound of the abdominal cavity, magnetic resonance cholangiopancreatography, gastroenterological complaints, quality of life were evaluated. Results. In patients taking ursodeoxycholic acid, the severity of gastroenterological complaints after cholecystectomy was less pronounced, blood lipid profile indicators improved. Conclusion. The appointment of a hepatoprotector based on ursodeoxycholic acid makes it possible to eliminate the phenomena of biliary dyspepsia, improves the blood lipid spectrum. The drug demonstrates high efficacy and safety, it can be recommended for the curation of patients with cholelithiasis who have undergone cholecystectomy.
About the Authors
K. N. Nadzhafova
Almazov National Medical Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
A. V. Kosheev
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Russian Federation
E. N. Kopysheva
Saint Petersburg State University
Russian Federation
Russian Federation
D. Yu. Butko
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
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For citations:
Nadzhafova K.N., Kosheev A.V., Kopysheva E.N., Butko D.Yu. The use of ursodeoxycholic acid preparations in the curation of patients in postcholecystectomy period: data from own observation. Experimental and Clinical Gastroenterology. 2025;(2):46-51. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-234-2-46-51
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