Incidence of iron deficiency and its pathogenesis in patients with H. pylori infection
https://doi.org/10.31146/1682-8658-ecg-187-3-130-135
Abstract
606 patients (405 men and 201 women) with HP infection were examined, 121 (m 67; f 54) found clinical or clinical and laboratory signs of iron deficiency, the frequency of iron deficiency in the examined group of patients with HP was 19.9% (16.8-23.3; CI 95%). 25 (20.7%) were diagnosed with anaemia, 66 (54.5%) patients had a latent deficit of iron, 30 patients (24.8%) showed only a decrease in TS, which is typical for pre-latent iron deficiency. 38 (31.4%) patients had a «true» iron deficiency, 44 (36.4%) patients had a combined variant of iron deficiency, and 39 (32.2%) iron deficiency developed as a result of chronic inflammation. There was a significant difference in the level of hepcidin in patients with different options for iron deficiency. In patients with “isolated” iron deficiency, it was 12.4 ± 2.3 ng/ml, vs 48.2-± 20.2 ng/ml vs 189.7 ± 31.1 ng / ml in patients with a combined pathogenic variant of iron deficiency and in patients with iron deficiency of chronic inflammation, respectively.
About the Authors
N. V. Shulyat’Eva
FGAOU VO First Moscow State Medical University. I. M. Sechenov, Ministry of Health of Russia (Sechenov University)
Russian Federation
Russian Federation
V. N. Drozdov
FGAOU VO First Moscow State Medical University. I. M. Sechenov, Ministry of Health of Russia (Sechenov University)
Russian Federation
Russian Federation
E. V. Shikh
FGAOU VO First Moscow State Medical University. I. M. Sechenov, Ministry of Health of Russia (Sechenov University)
Russian Federation
Russian Federation
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Review
For citations:
Shulyat’Eva N.V., Drozdov V.N., Shikh E.V. Incidence of iron deficiency and its pathogenesis in patients with H. pylori infection. Experimental and Clinical Gastroenterology. 2021;(3):130-135. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-187-3-130-135
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