Depending of quality of life and management patients in postcholecystectomy syndrome period on the nature of access, and functional safety of the sphincter of Oddi
https://doi.org/10.31146/1682-8658-ecg-180-8-54-58
Abstract
Objective. To evaluate the results of management and the quality of life in patients with postcholecystectomy syndrome depending on the functional condition of the sphincter of Oddi and the bile outflow.
Materials and methods. Quality of life was evaluated using the SF-36 questionnaire in 68 patients 1–3 years after examination and treatment of 116 patients with postcholecystectomy syndrome. The diagnosis was established with a scoring system for the data of clinical, laboratory and instrumental methods.
The dynamics of the bile outfl ow was determined by hepatobiliary scintigraphy (HBSG) on a Segams-9100 gamma cam-era using a 99mTc-bromeside for 90 minutes with a choleretic test.
A statistical study was carried out using the Statistica 10 computer program. The relationship of the signs was deter-mined by multivariate correlation analysis, and the correlation coefficients (r) were calculated. Differences in values were consideredsignifi cant at p <0.05.
Results. Patients after transabdominal operations compared with patients after endoscopic interventions had the best values of psychological (MH) (47.0 ± 2.8 versus 41.7 ± 2.3 p = 0.03) and physical (PH) (46.5 ± 2.4 versus 45.8 ± 2.1; p> 0.05) health components. The level of role functioning (RP) and vital activity (VT) in patients with timely bile outflow was higher than in patients with the sphincter Oddi‘s insufficiency (75.0 ± 11.0 versus 33.3 ± 13.2; p = 0.006 and 71, 3 ± 3.1 versus 58.9 ± 6.5; p = 0.005, respectively). In patients with the sphincter Oddi’s insufficiency the pain factor (BP) was reduced (62.7 ± 7.4 versus 79.1 ± 6.3, p = 0.02)
Conclusion. An objective assessment of the bile outflow and a differentiated correction of functional and organic disorders improve the quality of life in patients independently of the surgical approaches.
About the Authors
M. V. Repin
Perm State Medical University named after Academician E.A. Wagner (PSMU)
Russian Federation
Russian Federation
Maksim V. Repin - Department of advanced training; Professor, MD.
614000, Perm, st. Petropavlovskaya, 26
V. Yu. Mikryukov
Perm clinical hospital № 1
Russian Federation
Russian Federation
Vyacheslav Yu. Mikryukov - surgeon.
614077, Perm, Gagarina Boulevard, 68
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Review
For citations:
Repin M.V., Mikryukov V.Yu. Depending of quality of life and management patients in postcholecystectomy syndrome period on the nature of access, and functional safety of the sphincter of Oddi. Experimental and Clinical Gastroenterology. 2020;(8):54-58. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-180-8-54-58
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