Compelled feeding behavior: are patients ready to follow our recommendations?

The objective of this study was to determine whether feeding behavior and compliance with its modification are different between healthy respondents and those taking or potentially requiring of inhibitors of vitamin-K-epoxide reductase, considering the geographical specificity of diet. Material and methods. In open multicenter studies 196 respondents’ (88 men, 108 women) food preferences were assessed using questionnaires by NA Nikolaev (2015). Quantitative evaluation of compliance with lifestyle modification was studied with questionnaire. Results. There were no significant differences in consuming food either increasing (37,0 ± 19,5 points against 37,3 ± 17,98 points; Wald-Wolfowitz (Z), p = 0.16) or decreasing (62,2 ± 26,3 points against 63,4 ± 23,8 points; Wald-Wolfowitz (Z), p = 0.95) the efficiency of inhibitors of vitamin-K-epoxide reductase between the studied categories of respondents. The absence of differences persisted considering the geographical specificity of diet (104,9 ± 45,6 points vs. 100,7 ± 43,9 points; Wald-Wolfowitz (Z), p = 0.78). There was no connection between compliance with lifestyle modification and the actual diet modification in patients taking inhibitors of vitamin-K-epoxide reductase. Conclusions. Doctors’ recommendations of modifying feeding behavior are shown to be ineffective for patients taking inhibitors of vitamin-K-epoxide reductase. This may be an independent risk factor for complications either of proper treatment with these drugs or of underlying disease. Further clinical studies of patients’ compliance with feeding behavior modification are required.

диета, пищевое поведение, ингибиторы витамин-К-редуктазы, готовность к модификации, приверженность, diet, food behavior, inhibitors of vitamin-K-epoxide reductase, readiness for modification, commitment