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Experimental and Clinical Gastroenterology

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Analysis of the strain-specific effects of lactobacilli L. casei DG (L. paracasei CNCM I-1572) and the possibility of their use in clinical practice

https://doi.org/10.31146/1682-8658-ecg-162-2-151-158

Abstract

The effectiveness of probiotics is strain-specific. This paper presents the results of a systematic analysis of the promising lactobacterial strain Lactobacillus paracasei CNCM I-1572 (L. casei DG; L. paracasei DG). L. casei DG well survives in the conditions of the stomach and intestines, supports the beneficial microbiota and inhibits the growth of pathogenic bacteria, exhibits a therapeutic effect in ulcerative colitis, eradication of H. pylori, diverticular bowel disease, and irritable bowel syndrome.

About the Authors

I. Yu. Torshin
Big Data Storage and Analysis Center (CCHD), Moscow State University, Federal State Budget Educational Institution of Higher Education “Northern State Medical University” of the Ministry of Healthcare of the Russian Federation, FRC CSC RAS, Institute of Pharmacoinformatics
Russian Federation


O. A. Gromova
Big Data Storage and Analysis Center (CCHD), Moscow State University, FRC CSC RAS, Institute of Pharmacoinformatics
Russian Federation


V. A. Maksimov
Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuous Professional Education” of the Ministry of Healthcare of the Russian Federation
Russian Federation


I. N. Zacharova
Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuous Professional Education” of the Ministry of Healthcare of the Russian Federation
Russian Federation


S. I. Malavskaiya
Federal State Budget Educational Institution of Higher Education “Northern State Medical University” of the Ministry of Healthcare of the Russian Federation
Russian Federation


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For citations:


Torshin I.Yu., Gromova O.A., Maksimov V.A., Zacharova I.N., Malavskaiya S.I. Analysis of the strain-specific effects of lactobacilli L. casei DG (L. paracasei CNCM I-1572) and the possibility of their use in clinical practice. Experimental and Clinical Gastroenterology. 2019;(2):151-158. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-162-2-151-158

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ISSN 1682-8658 (Print)