Plasma Factors Of Hemostasis In The Peptic Ulcer Disease Associated With Arterial Hypertension

Abstract

The aim of the work is to study the indicators of coagulation and anticoagulant hemostasis, as well as fibrinolysis in patients with duodenal ulcer (DU) and arterial hypertension (AH) in order to predict and prevent possible complications. Materials and methods. The main group consisted of 18 patients with DU and AH 1-2 degree, stage II, high (3) group of cardiovascular risk (mean age 47.36±5.41 years). Comparison groups consisted of 22 patients with DU (mean age 40.53±4.28 years), 20 patients with AH (mean age 48.72±6.32 years) and 10 healthy people. Coagulation, anticoagulation and fibrinolytic components of hemostasis system were evaluated. Results. The hemostasis system in patients with UD and AH is characterized, it´s manifested by hypercoagulation, paracoagulation and a deficiency of fibrinolysis, which may be due to metabolic liver dysfunction