Ventilation Function Of Lungs, Content Of Phospholipids In Condensate Of Outdoor Air And Pressure In Pulmonary Artery In Smoking And Non-Smoking Patients With Liver Cirrhosis

Objective: To study the ventilation function of the lungs and the phospholipids of exhaled air in smoking and non-smoking patients with cirrhosis of the liver (CP) in a comparative aspect. Material and methods: 49 patients with portal hypertension (GHG) and 20 healthy volunteers were examined. Spirography was carried out with the help of the hardware-software complex “VALENTA”. The KVV was collected according to the recommendations of GI Sidorenko. in the morning after rinsing the mouth. The volume of KVB and the concentration of total phospholipids in 1 ml of KVB (OFL, mmol / L) were measured. Phospholipids were extracted by the Blur method. The statistics were implemented using the application software “Statistica for Windows, Release 6.0.” Results of the study and their discussion: In patients with CP, a significant decrease in the ventilation capacity of the lungs was more pronounced in smokers, as well as a decrease in the amount of condensate in the exhaled air (KVV) and phospholipids in KVV. The average pressure in the pulmonary artery with CP was higher than in the healthy. Conclusion: Smokers with pulmonary embolism are more severely affected by pulmonary ventilation than non-smokers. There is no significant difference in the decrease in the amount of phospholipids in the exhaled air from smokers and non-smoking patients with CP.

цирроз печени, спирометрия, фосфолипиды выдыхаемого воздуха, давление в легочной артерии, курящие, некурящие, cirrhosis of the liver, spirometry, phospholipids of exhaled air, pulmonary artery pressure, smoking, non-smoking