ИНФЕКЦИЯ HELICOBACTER PYLORI И МЕТАБОЛИЧЕСКИЕ НАРУШЕНИЯ: ЕСТЬ ЛИ СВЯЗЬ?
Аннотация
В статье представлен обзор современных исследований, посвященных изучению роли Helicobacter pylori (как одного из наиболее известных и широко распространенных бактериальных агентов) в патогенезе метаболического синдрома. Однако результаты научных работ иногда противоречивы, что диктует необходимость проведения дальнейших исследований для уточнения особенностей влияния Helicobacter pylori в формировании различных компонентов метаболического синдрома.
Об авторах
Ю. П. Успенский
Санкт-Петербургский государственный Педиатрический медицинский университет; Первый Санкт-Петербургский государственный медицинский университет имени И. П. Павлова; СПб ГБУЗ «Елизаветинская больница»
Россия
Россия
Н. В. Барышникова
Первый Санкт-Петербургский государственный медицинский университет имени И. П. Павлова; Институт экспериментальной медицины ФАНО; СПб ГБУЗ «Елизаветинская больница»
Россия
Россия
Список литературы
1. Lakka H. M. The metabolic syndrome and total cardiovascular disease mortality in middle-aged men / H. M. Lakka, D. E. Laaksonen, T. A. Lakka // JAMA. - 2002. - Vol. 4, N. 21. - P. 2709-2716.
2. Franceschi F., Annalisa T., Teresa D. R., et al. Role of Helicobacter pylori infection on nutrition and metabolism. World J Gastroenterol 2014; 20: 12809-17.
3. Kountouras J., Polyzos S. A., Zavos C., et al. Helicobacter pylori might contribute to nonalcoholic fatty liver disease-related cardiovascular events by releasing prothrombotic and proinflammatory factors. Hepatology 2014; 60: 1450-1.
4. Polyzos S. A., Kountouras J., Zavos C., Deretzi G. Helicobacter pylori infection, insulin resistance and nonalcoholic fatty liver disease. Med Hypotheses 2014; 82: 795.
5. Vijayvergiya R., Vadivelu R. Role of Helicobacter pylori infection in pathogenesis of atherosclerosis. World J Cardiol 2015; 7: 134-43.
6. Chen T. P., Hung H. F., Chen M. K. et al. Helicobacter pylori infection is positively associated with metabolic syndrome in Taiwanese adults: a cross-sectional study. Helicobacter 2015; 20: 184-91.
7. Rasmi Y. Possible role of Helicobacter pylori infection via microvascular dysfunction in cardiac syndrome X / Y. Rasmi, S. Raeisi // Cardiology Journal. - 2009. - Vol. 6. - P. 585-587
8. Pellicano R. Helicobacter pylori and insulin resistance: time to do interventional studies / R. Pellicano, M. Rizzetto // Digestive Diseases and Sciences. - 2009. - Vol.54(12). - P. 2765-2766
9. Strachan D. P. Non-gastrointestinal consequences of Helicobacter pylori infection / D. P. Strachan // British Medical Bulletin. - 1998. - Vol. 54(1). - P. 87-93
10. Kayar Y., Pamukçu Ö., Eroğlu H., Kalkan Erol K., Ilhan A., Kocaman O. Relationship between Helicobacter pylori Infections in Diabetic Patients and Inflammations, Metabolic Syndrome, and Complications. Int J Chronic Dis.2015;2015:290128.
11. Martin S. S. Leptin resistance: a possible interface of inflammation and metabolism in obesity related cardiovascular disease / S. S. Martin // J Am Coll Cardiol. - 2008. - Vol.52(15). - P. 1201-1210.
12. Успенский Ю. П., Суворов А. Н., Барышникова Н. В. Инфекция Helicobacter pylori в клинической практике. СПб.: ИнформМед, 2011. - 572 с.
13. Stec-Michalska K., Malicki S., Michalski B. et al. Gastric ghrelin in relation to gender, stomach topography and Helicobacter pylori in dyspeptic patients // World J Gastroenterol. - 2009. - Vol. 15(43). - P. 5409-5917.
14. Konturek P. C., Cześnikiewicz-Guzik M., Bielanski W., Konturek S. L. Involvement of Helicobacter pylori infection in neuro-hormonal control of food intake// J Physiol Pharmacol. - 2006. - Vol. 57(5). - P. 67-81.
15. Isomoto H., Ueno H., Nishi Y., Wen C. Y. / Impact of Helicobacter pylori infection on ghrelin and various neuroendocrine hormones in plasma // World J Gastroenterol. - 2005. - Vol. 11. - P. 1644-1648.
16. Новоселя Н. В. Состояние пищевого статуса и адипокино-цитокинового гомеостаза у больных с хроническими заболеваниями гастропанкреатодуоденального комплекса: автореф.дис. …докт. мед.наук: 14.00.05: защищена 27.11.09 / Н. В. Новоселя. - Владикавказ, 2009. - 40 с.
17. Suzuki H., Masaoka T., Hosoda H. et al. Plasma ghrelin concentration correlates with the levels of serum pepsinogen I and pepsinogen I/II ratio - a possible novel and non-invasive marker for gastric atrophy // Hepatogastroenterology. - 2004. - Vol.51(59). - P. 1249-1254.
18. Pacifico L., Anania C., Osborn J. F. et al. Long-term effects of Helicobacter pylori eradication on circulating ghrelin and leptin concentrations and body composition in prepubertal children // Eur J Endocrinol. - 2008. - Vol.158(3). - P. 323-332.
19. Masaoka T., Suzuki H., Imaeda H. et al. Long-term strict monitoring of plasma ghrelin and other serological markers of gastric diseases after Helicobacter pylori eradication // Hepatogastroenterology. - 2005. - Vol. 52(61). - P. 1-4.
20. Jeffery P. L. et al. Endocrine impact of Helicobacter pylori: Focus on ghrelin and ghrelin o-acyltransferase // World J Gastroenterol. - 2011. - Vol. 17(10). - P. 1249-1260.
21. Jang E. J., Park S. W., Park J. S. et al. The influence of the eradication of Helicobacter pylori on gastric ghrelin, appetite, and body mass index in patients with peptic ulcer disease // J Gastroenterol Hepatol. - 2008. - Vol.23(2). - P. 278-285.
22. Li Q., Zhang J., Zhou Y., Qiao L. Obesity and gastric cancer. Front Biosci (Landmark Ed). 2012;17:2383-90.
23. Polyzos S. A., Kountouras J., Zavos C., Deretzi G. The association between Helicobacter pylori infection and insulin resistance: a systematic review. Helicobacter 2011; 16: 79-88.
24. Eshraghian A., Hashemi S. A., Hamidian Jahromi A. et al. Helicobacter pylori infection as a risk factor for insulin resistance // Digestive Diseases and Sciences. - 2009. - Vol.54(9). - P. 1966-1970.
25. Gen R. Effect of Helicobacter pylori eradication on insulin resistance, serum lipids and low-grade inflammation / R. Gen, M. Demir, H. Ataseven // Southern Medical Journal. - 2010. - Vol. 103(3). - P. 190-196.
26. Dogan Z, Sarikaya M, Ergul B, Filik L. The effect of Helicobacter pylori eradication on insulin resistance and HbA1c level in people with normal glucose levels: a prospective study. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2014;159:242-5.
27. Yang GH, Wu JS, Yang YC, Huang YH, Lu FH, Chang CJ. Gastric Helicobacter pylori infection associated with risk of diabetes mellitus, but not prediabetes. J Gastroenterol Hepatol 2014;29:1794-9
28. Rekwal L, Misra SP, Misra V, Yadav RK, Srivastava A. Association of Helicobacter pylori infection with type 2 diabetes. Indian J Endocrinol Metab 2014;18:694-9
29. Horikawa C, Kodama S, Fujihara K, et al. High risk of failing eradication of Helicobacter pylori in patients with diabetes: a meta-analysis. Diabetes Res Clin Pract 2014;106:81-7
30. Vafaeimanesh J, Parham M, Seyyedmajidi M, Bagherzadeh M. Helicobacter pylori infection and insulin resistance in diabetic and nondiabetic population. Sci World J 2014;2014:391250
31. Marietti M, Gasbarrini A, Saracco G, Pellicano R. Helicobacter pylori infection and diabetes mellitus: the 2013 state of art. Panminerva Med 2013;55:277-81
32. Шишкин А. Н. Диабетическая гастропатия. Проблемы и решения / А. Н. Шишкин, Д. В. Кирилюк // Новые Санкт-Петербургские врачебные ведомости. - 2007. - № 1. - С. 54-58
33. Gillum R. F. Infection with Helicobacter pylori, coronary heart disease, cardiovascular risk factors, and systemic inflammation: the Third National Health and Nutrition Examination Survey / R. F. Gillum // Journal of the National Medical Association. - 2004. - Vol.96(11). - P. 1470-1476
34. Hamed S. A., Amine N. F., Galal G. M. et al. Vascular risks and complications in diabetes mellitus: the role of Helicobacter pylori infection // Journal of Stroke and Cerebrovascular Diseases. - 2008. - Vol.17(2). - P. 86-94.
35. Diabetes mellitus and Helicobacter pylori infection / M. P. Dore, M. Bilotta, H. M. Malaty et al. // Nutrition. - 2000. - Vol.16(6). - P. 407-410.
36. Type 2 diabetes mellitus: A risk factor for Helicobacter pylori infection: A hospital based case-control study / B. R. Devrajani, S. Z. Shah, A. A. Soomro, T. Devrajani // International Journal of Diabetes in Developing Countries. - 2010. - Vol.30(1). - P. 22-26
37. Type 2 diabetes mellitus affects eradication rate of Helicobacter pylori / M. Sargýn, O. Uygur-Bayramicli, H. Sargýn et al. // World Journal of Gastroenterology. - 2003. - Vol.9(5). - P. 1126-1128.
38. Longo-Mbenza B. Prevention of the metabolic syndrome insulin resistance and the atherosclerotic diseases in Africans infected by Helicobacter pylori infection and treated by antibiotics / B. Longo-Mbenza, J. Nkondi Nsenga, D. Vangu Ngoma // International Journal of Cardiology. - 2007. - Vol. 121(3). - P. 229-238.
39. Association of Helicobacter pylori infection with elevated serum lipids / A. Laurila, A. Bloigu, S. Näyhä et al. // Atherosclerosis. - 1999. - Vol.142 (1). - P. 207-210
40. Eradication of Helicobacter pylori increases the incidence of hyperlipidaemia and obesity in peptic ulcer patients / T. Kamada, J. Hata, H. Kusonoki et al. // Dig Liver Dis. - 2005. - Vol. 37. - P. 39-43
41. Francesco Franceschi, Antonio Gasbarrini, Stergios A. Polyzos, Jannis Kountouras Extragastric Diseases and Helicobacter pylori //Helicobacter. 2015. Volume 20, Issue S 1. Pages 40-46
42. Павлов О. Н. Носительство Helicobacter pylori как скрытый системный фактор риска // Медицинский альманах. - 2011. - № 4 (17). - С. 125-130.
43. Nikolopoulou A., Tousoulis D., Antoniades C. et al. Common community infections and the risk for coronary artery disease and acute myocardial infarction: evidence for chronic overexpression of tumor necrosis factor alpha and vascular cells adhesion molecule-1 // Int J Cardiol. - 2008. - Vol. 130. - P. 246-250.
44. Figura N., Franceschi F., Santucci A. et al. Extragastric Manifestations of Helicobacter pylori Infection // Helicobacter. - 2010. - Vol. 15, suppl.1. - P. 60-68.
45. Ayada K., Yokota K., Hirai K. et al. Regulation of cellular immunity prevents Helicobacter pylori-induced atherosclerosis // Lupus. - 2009. - Vol. 18. - P. 1154-1168.
46. Szklo M., Ding J., Tsai M. Y. et al. Individual pathogens, pathogen burden and markers of subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis // J Cardiovasc Med (Hagerstown). - 2009. - Vol. 10. - P. 747-751.
47. Honda C., Adachi K., Arima N. et al. Helicobacter pylori infection does not accellerate the age-related progression of arteriosclerosis: a 4-year follow-up study // J Gastroenterol Hepatol. - 2008. - Vol. 23. - P. 373-378.
48. Tamer G. S., Tengiz I., Ercan E. et al. Helicobacter pylori seropositivity in patients with acute coronary syndromes // Dig Dis Sci. - 2009. - Vol. 54. - P. 1253-1256.
49. Jha H. C., Prasad J., Mittal A. High immunoglobulin A seropositivity for combined Chlamydia pneumoniae, Helicobacter pylori infection, and high-sensitivity C-reactive protein in coronary artery disease patients in India can serve as atherosclerotic marker // Heart Vessels. - 2008. - Vol. 23. - P. 390-396.
50. Pasceri V., Cammarota G., Patti G. et al. Association of virulent Helicobacter pylori strains with ischemic heart disease// Circulation. - 1998. - Vol. 97(17). - P. 1675-1679.
51. Kowalski M. Helicobacter pylori (H. pylori) infection in coronary artery disease: influence of H. pylori eradication on coronary artery lumen after percutaneous transluminal coronary angioplasty. The detection of H. pylori specific DNA in human coronary atherosclerotic plaque // Journal of Physiology and Pharmacology. - 2001. - Vol. 1, suppl 1. - P. 3-31.
52. Zhang S., Guo Y., Ma Y., Teng Y. Cytotoxin-associated gene-Aseropositive virulent strains of Helicobacter pylori and atherosclerotic disease: a systematic review // Chin Med J. - 2008. - Vol. 121. - P. 946-951.
53. Franceschi F., Niccoli G., Ferrante G. et al. CagA antigen of Helicobacter pylori and coronary instability: insight from a clinico-pathological study and a meta-analysis of 4241 cases // Atherosclerosis. - 2009. - Vol. 202. - P. 535-542.
54. Льнявина В. М. Изменения липидного обмена у больных ишемической болезнью сердца, ассоциированной с дисбиозом кишечника; метаболические эффекты пробиотиков // Автореф. дисс… к. м. н. - СПб, 2009. - 24 с.
55. Pellicano R., Mazzarello M. G., Morelloni S. et al. Acute myocardial infarction and Helicobacter pylori seropositivity// International Journal of Clinical and Laboratory Research. - 1999. - Vol. 29(4). - P. 141-144.
56. Fraser A. G., Scragg R. K., Cox B., Jackson R. T. Helicobacter pylori, Chlamydia pneumoniae and myocardial infarction // Intern Med J. - 2003. - Vol. 33(7). - P. 267-272.
57. Alkout A. M., Ramsay E. J., Mackenzie D. A. et al. Quantitative assessment of IgG antibodies to Helicobacter pylori and outcome of ischaemic heart disease// FEMS Immunology and Medical Microbiology. - 2000. - Vol. 29(4). - P. 271-274.
58. Liu J, Wang F, Shi S. Helicobacter pylori infection increase the risk of myocardial infarction: a meta-analysis of 26 studies involving more than 20,000 participants. Helicobacter 2014. https://doi.org/10.1111/hel.12188
59. Polyzos SA, Kountouras J, Papatheodorou A, et al. Helicobacter pylori infection in patients with nonalcoholic fatty liver disease. Metabolism 2013;62:121-6.
60. Polyzos SA, Nikolopoulos P, Stogianni A, et al. Effect of Helicobacter pylori eradication on hepatic steatosis, NAFLD fibrosis score and HSENSI in patients with nonalcoholic steatohepatitis: a MR imaging-based pilot open-label study. Arq Gastroenterol 2014;51:261-8.
Рецензия
Для цитирования:
Успенский Ю.П., Барышникова Н.В. ИНФЕКЦИЯ HELICOBACTER PYLORI И МЕТАБОЛИЧЕСКИЕ НАРУШЕНИЯ: ЕСТЬ ЛИ СВЯЗЬ? Экспериментальная и клиническая гастроэнтерология. 2017;(7):107-114.
For citation:
Uspenskiy Yu.P., Baryshnikova N.V. HELICOBACTER PYLORI INFECTION AND METABOLIC DISORDERS: IS THE LINK? Experimental and Clinical Gastroenterology. 2017;(7):107-114. (In Russ.)
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