Микробиота полости рта и гастроэнтерологические заболевания: гипотетическое «путешествие» пародонтальной микробиоты на «пародонтально-гастроэнтерологическом экспрессе» по маршруту рот-кишечник

Исследования и публикации последнего десятилетия кардинально меняют традиционные медицинские представления и наше понимание о возможной взаимосвязи органов и систем организма. Так, множество исследований посвящено изучению связи микробиома кишечника и различных заболеваний. Определенное влияние на микробиом кишечника оказывает микробиом полости рта. Данный обзор, основанный на опубликованных источниках из баз Pubmed и Scopus, в которых рассматривалась взаимосвязь пародонтальной микробиоты/заболеваний пародонта и гастроэнтерологических заболеваний, представляет расширенную версию доклада на круглом столе Научного общества гастроэнтерологов России 20 июня 2025 года. В рамках гипотетического «путешествия» пародонтальной микробиоты на «пародонтально-гастроэнтерологическом экспрессе» по маршруту рот-кишечник рассмотрено возможное влияние пародонтальной микробиоты и заболеваний пародонта на развитие гастроэнтерологических заболеваний. Результаты эпидемиологических, экспериментальных и клинических исследований свидетельствуют, что пародонтопатические бактерии могут принимать участие в развитии онкологических заболеваний желудочно-кишечного тракта, язвенной болезни, воспалительных заболеваний кишечника и неалкогольной жировой болезни печени.

микробиота полости рта, болезни пародонта, ось рот-кишечник, рак пищевода, рак желудка, колоректальный рак, язвенная болезнь, воспалительные заболевания кишечника, неалкогольная жировая болезнь печени

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