Features of the course of the early period of primary tuberculosis infection in a patient with Hurler syndrome: tactics of managing a comorbid patient

Abstract

A clinical case of a child with comorbid pathology demonstrates the high importance of alertness of specialists of various profiles of the pediatric network. Doctors of the pediatric phthisiology network are of no small importance, since in children with genetic diseases, tuberculosis can proceed under the «masks» of other pathologies. Mucopolysaccharidosis type I (MPS I) is a rare genetic disease caused by a mutation of the IDUA gene, which encodes the enzyme alpha-L-iduronidase. Hurler syndrome, which is the most severe form of MPS I, requires special attention to prevent the development of severe complications, which often lead to death.