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Post-COVID syndrome: myth or reality

https://doi.org/10.31146/1682-8658-ecg-238-6-118-128

Abstract

The purpose of the study: to attract the attention of pediatricians, neurologists and other specialties to the problem of the state of neurological and somatic statuses in children who have suffered SARS-COV-2. Materials and methods. A review of literature was carried out, 5 years depth of search, regarding the formation of asthenic and psychosomatic syndromes in the post -shaped period, as well as the influence of the latter on cognitive functions and the quality of life of the child. Results. In the period from December 2019 to January 2020, the world community collided with the 2019 coronavirus infection pandemia (Covid-19) caused by SARS-COV-2 Betacoronaviros. According to annual reports, the incidence is stored on high numbers. As of June 2025, 776 007 137 cases of disease were registered in the world, 7 059 612 deaths. UNICEF data indicate that children and adolescents accounted for 0.4% of all registered deaths (> 17 400 cases), of which 53% among children and adolescents 10-19 years old, 47% among children 0-9 years old. In the Russian Federation, according to information from the state report, in 2021-9.054 million cases of the disease were recorded, in 2022 12.102 million, in 2023-2.072 million, in 2024-1.125 million cases. This virus has a high degree of virulence and is capable of aggressively to affect the epithelial cells not only of the upper respiratory tract, But also the stomach, intestines, brain, which determines the variety of its clinical manifestations. Currently, in the structure of clinical manifestations, a decrease in lung lesions so, in 2021, the share of pneumonia was 22%, in 2022-4.6%, in 2023-4.1%, in 2024-3,2%. In childhood, despite the easier course, the disease is accompanied by a systemic lesion - multi -inflammatory syndrome (MVS). The penetration of the SARS-COV-2 through the hematoencephalic barrier contributes to the formation of neurological symptoms: headache, acute encephalopathy, convulsions, weakness, anosmia, etc. Most of them remain for a long period. Meanwhile, a state, which is characterized by weakness, fatigue, emotional lability, hyperesthesia, sleep disturbances and other somatovegetative manifestations, is included in the concept of asthenic syndrome. Asthenia can be observed with somatic, infectious and other diseases. The analysis of literary data emphasizes the importance of studying neurological symptoms in children who have suffered COVID-19, depending on age and require additional attention. Further studies are needed for a better understanding of these manifestations, timely diagnosis and development of effective approaches to treatment. Conclusion. The course of SARS, caused by SARS -COV -2 is accompanied by the formation of asthenic syndrome, which is one of the clinical forms of manifestation of post -shoe syndrome. Asthenia is accompanied by the depletion of energy resources, registered in all age periods, is preserved for a long time and requires correction. The study of the microcirculatory channel performed by G. NATALELLO in patients with coronavirus pneumonia and our studies of auto -regulation of intracranial blood flow after the SARS -COV -2 auto -regulation, accompanied in the first case of micro -vascular disorders in the form of microcircuctions and microtrombosis and damage to the neurovascular unity and The development of the AC is a morphological substrate formation of post -shoe syndrome in children. Thus, for the diagnosis of post -shoe syndrome, it is necessary to perform a complex of clinical and instrumental studies, which will determine approaches to rehabilitation of children who have undergone SARS -COV -2.

About the Authors

S. N. Novoselova
N.I. Pirogov Russian National Research Medical University
Russian Federation


L. A. Kharitonova
N.I. Pirogov Russian National Research Medical University
Russian Federation


O. V. Papisheva
N.I. Pirogov Russian National Research Medical University
Russian Federation


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Novoselova S.N., Kharitonova L.A., Papisheva O.V. Post-COVID syndrome: myth or reality. Experimental and Clinical Gastroenterology. 2025;(6):118-128. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-238-6-118-128

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