Тромбоэмболические осложнения у детей с воспалительными заболеваниями кишечника

Воспалительные заболевания кишечника (ВЗК), к которым относятся язвенный колит (ЯК) и болезнь Крона (БК), являются системным заболеванием, для них характерны внекишечные проявления и различные осложнения. Тромбоэмболические осложнения (ТЭО), включая венозные и артериальные поражения, являются редким внекишечным проявлением ВЗК и изучены недостаточно. У взрослых пациентов с ВЗК ТЭО встречается чаще в три раза, по сравнению с общей популяцией, а во время обострения заболевания их относительный риск возрастает в 15 раз. По данным литературы у детей с ВЗК ТЭО выявляется до 3% случаев. Факторами риска тромбоза являются форма ВЗК (чаще ЯК) и активность заболевания, личный и семейный анамнез тромбоза, а также традиционные факторы риска сосудистых осложнений. Церебральный венозный тромбоз (ЦВТ) - самый серьезный вид ТЭО и чаще встречается у детей. В литературе имеется множество сообщений о развитии ЦВТ на фоне ВЗК у детей, в то же время отсутствуют единые рекомендации о ведении этих пациентов. Целью исследования явилось обобщение и анализ современных данных о частоте ТЭО у детей с ВЗК.

воспалительные заболевания кишечника, язвенный колит, болезнь Крона, тромбоэмболические осложнения, церебральный венозный тромбоз, инсульт, дети

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