Cholecystectomy effect on the digestive system
https://doi.org/10.31146/1682-8658-ecg-234-2-234-242
Abstract
Cholecystectomy continues to be the main method of treating gallstone disease. This is one of the most frequent surgical procedures in the world. Despite the continuous improvement of techniques and good surgical results, the consequences of cholecystectomy for the physiology of the gastrointestinal tract and metabolism in general can be unfavorable. In the absence of a gallbladder, the mechanics of digestion change, which affects the condition of the digestive tube, hepatobiliary system, and pancreas. In addition, without a gallbladder, the body suffers from the modulation of the flow of bile acids, which normally should compensate for the metabolic stress caused by eating. The article highlights the most important aspects of the effect of cholecystectomy on the gastrointestinal tract, the mechanisms of these effects and the results of modern research on these issues.
About the Authors
K. N. Nadzhafova
Almazov National Medical Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
A. A. Gnutov
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
O. A. Kizimova
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Ya. V. Sousova
Almazov National Medical Research Centre of the Ministry of Health of the Russian Federation; St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Yu. A. Fominykh
Almazov National Medical Research Centre of the Ministry of Health of the Russian Federation; St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
A. M. Mayorova
Almazov National Medical Research Centre of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
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For citations:
Nadzhafova K.N., Gnutov A.A., Kizimova O.A., Sousova Ya.V., Fominykh Yu.A., Mayorova A.M. Cholecystectomy effect on the digestive system. Experimental and Clinical Gastroenterology. 2025;(2):234-242. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-234-2-234-242
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