Negative effects of vaping on the condition of the mucous membrane of the stomach and duodenum

The aim. To investigate the condition of the mucous membrane of the stomach and duodenum in users of electronic nicotine delivery systems Materials and methods. The study involved 34 people. Conducted: testing using questionnaires (a specially designed questionnaire to identify the fact of smoking, GSRS to identify dyspeptic symptoms), esophagogastroduodenoscopy to determine the condition of the gastric mucosa, histological examination of the materials obtained, determination of the Helicobacter pylori antigen using an immunochromatographic test system. According to the results of the survey, the participants were divided into 2 groups: people who use electronic cigarettes and non-smokers. Results. The intensity of gastroenterological symptoms measured using the GSRS questionnaire was significantly higher in vapers. The conducted studies have shown the presence of pathological changes in the mucous membrane of the stomach and duodenum in all users of electronic cigarettes. During the endoscopic examination, cardiac sphincter insufficiency was most often recorded, which is associated with the effect of cigarette components on the tone of the lower esophageal sphincter. According to the results of histological examination, 90% of e-cigarette users showed signs of chronic inflammation of the gastric mucosa. Half of these users also had atrophy of the gastric mucosa. The data of the immunochromatographic test for the Helicobacter pylori antigen in stool samples from e-cigarette users confirm the functional nature of the detected disorders. Conclusion. The study allowed us to collect objective information about the condition of the gastric mucosa and duodenum in active users of electronic cigarettes. The negative effects of e-cigarette components on the mucous membrane of the stomach and duodenum have been established.

Electronic cigarettes, vaping, gastrointestinal tract, esophagogastroduodenoscopy, GSRS

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