Preview

Experimental and Clinical Gastroenterology

Advanced search

A case of Clostridium difficile infection as a complication of antibiotic therapy

https://doi.org/10.31146/1682-8658-ecg-226-6-225-228

Abstract

This clinical case demonstrates the complexity of managing a comorbid patient with antibiotic-associated diarrhea. We observed a patient who, during therapy, developed extremely early premature birth with a live premature fetus (at 25-26 weeks), antibiotic-associated (Clostridium difficile) intractable diarrhea, pseudomembranous colitis, and acute dynamic intestinal obstruction. After treatment for 14 days, the patient’s condition improved.

About the Authors

L. P. Faizova
Bashkir State Medical University
Russian Federation


D. Kh. Kalimullina
Bashkir State Medical University
Russian Federation


S. V. Fedorov
Bashkir State Medical University
Russian Federation


V. U. Sataev
Kazan State Medical Academy - Branch Campus of the FSBEI FPE RMACPE
Russian Federation


E. A. Gaisina
Republican Clinical Hospital named after G. G. Kuvatov
Russian Federation


L. T. Akhmetova
Republican Clinical Hospital named after G. G. Kuvatov
Russian Federation


Yu. R. Khaibullina
Republican Clinical Hospital named after G. G. Kuvatov
Russian Federation


Yu. K. Ayupova
Republican Clinical Hospital named after G. G. Kuvatov
Russian Federation


References

1. Ardatskaya M.D., Topchiy T. B., Butorova L. I. and others. Antibiotic-associated intestinal lesions in the practice of a clinician: a manual for doctors. Moscow. Prima Print, 2020. 53 p.: ill., tab. (in Russ.) ISBN 978-5-6042241-9-9.@@ Ардатская М. Д., Топчий Т. Б., Буторова Л. И. и другие. Антибиотико-ассоциированные поражения кишечника в практике клинициста: пособие для врачей. М.: Прима Принт, 2020. - 53 с.: ил., таб. - ISBN 978-5-6042241-9-9.

2. Ivashkin V. T., Yushchuk N. D., Mayev I. V. et al. Diagnostics and treatment of Clostridium difficile-associated disease: Guidelines of the Russian gastroenterological association.Russian Journal of Gastroenterology, Hepatology, Coloproctology. 2016;26(5):56-65. (In Russ.) doi: 10.22416/1382-4376-2016-5-56-65.@@ Ивашкин В. Т., Ющук Н. Д., Маев И. В. и др. Рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению Clostridium difficile-ассоциированной болезни. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2016;26(5):56-65. doi: 10.22416/1382-4376-2016-5-56-65.

3. Drapkina O. M., Lazebnik L. B., Bakulin I. G. et al. Clostridioides difficile infection: diagnosis, treatment, and prevention Clinical guidelines of the Russian Scientific Medical Society of Internal Medicine, the Gastroenterological Scientific Society of Russia, and the North- West Society of Gastroenterologists and Hepatologists. Experimental and Clinical Gastroenterology. 2023;(2):4-32. (In Russ.) doi: 10.31146/1682-8658-ecg-210-2-4-32.@@ Драпкина О. М., Лазебник Л. Б., Бакулин И. Г., Журавлева М. С. Инфекция Clostridium difficile: диагностика, лечение и профилактика. Экспериментальная и клиническая гастроэнтерология. 2023;(2):4-32. doi: 10.31146/1682-8658-ecg-210-2-4-32.

4. Nikolaeva I. V., Shestakova I. V., Murtazina G. K. Current strategies for diagnosis and treatment of Clostridium difficile-infection (literature review). Acta Biomedica Scientifica. 2018;3(1):34-42. (In Russ.) doi: 10.29413/ABS.2018-3.1.5.@@ Николаева И. В., Шестакова И. В., Муртазина Г. Х. Современные стратегии диагностики и лечения Clostridium difficile-инфекции (обзор литературы). Acta Biomedica Scientifica. 2018;3(1):34-42. doi: 10.29413/ABS.2018-3.1.5.

5. [Internet resource] available at: https://www.eduherald.ru/pdf/2018/6/19253.pdf Accessed 05/05/2024.@@ Электронный ресурс https://www.eduherald.ru/pdf/2018/6/19253.pdf

6. ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections. Am J Gastroenterol. 2021;116:1124-1147. doi: 10.14309/ajg.0000000000001278.

7. Said Fadi Yassin, Chief Editor: John Geibel. Рseudomembranous Colitis Surgery Treatment & Management. Medscape. Updated: Feb 16, 2023.

8. European Society of Clinical Microbiology and Infectious Diseases: 2021 update on the treatment guidance document for Clostridioides difficile infection in adults // Joffrey van Prehn, Elena Reigadas, Erik H. Vogelzang, Fidelma Fitzpatrick, Ed J. Kuijper. Open AccessPublished: October 19, 2021. doi: 10.1016/j.cmi.2021.09.038.


Review

For citations:


Faizova L.P., Kalimullina D.Kh., Fedorov S.V., Sataev V.U., Gaisina E.A., Akhmetova L.T., Khaibullina Yu.R., Ayupova Yu.K. A case of Clostridium difficile infection as a complication of antibiotic therapy. Experimental and Clinical Gastroenterology. 2024;(6):225-228. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-226-6-225-228

Views: 149


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1682-8658 (Print)