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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-226-6-225-228</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-2824</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Случай инфекции Clostridium difficile, как осложнение антибиотикотерапии</article-title><trans-title-group xml:lang="en"><trans-title>A case of Clostridium difficile infection as a complication of antibiotic therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-8266-2915</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фаизова</surname><given-names>Л. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Faizova</surname><given-names>L. P.</given-names></name></name-alternatives><email xlink:type="simple">ofaizov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7187-2533</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калимуллина</surname><given-names>Д. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalimullina</surname><given-names>D. Kh.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6106-0301</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федоров</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorov</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8641-7875</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сатаев</surname><given-names>В. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Sataev</surname><given-names>V. U.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-5070-5362</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гайсина</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gaisina</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-4984-5119</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахметова</surname><given-names>Л. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhmetova</surname><given-names>L. T.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-2176-1067</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хайбуллина</surname><given-names>Ю. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Khaibullina</surname><given-names>Yu. R.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-3862-9883</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аюпова</surname><given-names>Ю. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Ayupova</surname><given-names>Yu. K.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ «Башкирский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Казанская государственная медицинская академия - филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical Academy - Branch Campus of the FSBEI FPE RMACPE</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>БУЗ МЗ РБ «Республиканская клиническая больница имени Г. Г. Куватова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republican Clinical Hospital named after G. G. Kuvatov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>22</day><month>10</month><year>2024</year></pub-date><volume>0</volume><issue>6</issue><fpage>225</fpage><lpage>228</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фаизова Л.П., Калимуллина Д.Х., Федоров С.В., Сатаев В.У., Гайсина Э.А., Ахметова Л.Т., Хайбуллина Ю.Р., Аюпова Ю.К., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Фаизова Л.П., Калимуллина Д.Х., Федоров С.В., Сатаев В.У., Гайсина Э.А., Ахметова Л.Т., Хайбуллина Ю.Р., Аюпова Ю.К.</copyright-holder><copyright-holder xml:lang="en">Faizova L.P., Kalimullina D.K., Fedorov S.V., Sataev V.U., Gaisina E.A., Akhmetova L.T., Khaibullina Y.R., Ayupova Y.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/2824">https://www.nogr.org/jour/article/view/2824</self-uri><abstract><p>Данный клинический случай демонстрирует сложность ведения коморбидного пациента с антибиотик-ассоциированной диареей. Мы наблюдали пациентку, у которой на фоне терапии развились экстремально ранние преждевременные роды живым недоношенным плодом (гистационный возраст 25-26 недель), антибиотико-ассоциированная (Clostridium difficile) не купируемая диарея, псевдомембранозный колит, острая динамическая кишечная непроходимость. На фоне лечения в течение 14 суток состояние пациентки улучшилось.</p></abstract><trans-abstract xml:lang="en"><p>This clinical case demonstrates the complexity of managing a comorbid patient with antibiotic-associated diarrhea. We observed a patient who, during therapy, developed extremely early premature birth with a live premature fetus (at 25-26 weeks), antibiotic-associated (Clostridium difficile) intractable diarrhea, pseudomembranous colitis, and acute dynamic intestinal obstruction. After treatment for 14 days, the patient’s condition improved.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>антибиотико-ассоциированная (Clostridium difficile) диарея</kwd><kwd>псевдомембранозный колит</kwd><kwd>«клинический случай»</kwd></kwd-group><kwd-group xml:lang="en"><kwd>antibiotic-associated (Clostridium difficile) diarrhea</kwd><kwd>pseudomembranous colitis</kwd><kwd>“clinical case”</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ardatskaya M.D., Topchiy T. B., Butorova L. I. and others. Antibiotic-associated intestinal lesions in the practice of a clinician: a manual for doctors. Moscow. Prima Print, 2020. 53 p.: ill., tab. (in Russ.) ISBN 978-5-6042241-9-9.@@ Ардатская М. Д., Топчий Т. Б., Буторова Л. И. и другие. Антибиотико-ассоциированные поражения кишечника в практике клинициста: пособие для врачей. 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