Digestive system and mitochondrial diseases in children
O. I. Gumeniuk,
I. A. Glushakov,
Yu. V. Chernenkov,
I. A. Bochkarev,
G. V. Gafurova,
E. E. Sukhushina https://doi.org/10.31146/1682-8658-ecg-226-6-43-46
Abstract
The article discusses the features of lesions of the digestive system in children with mitochondrial diseases. Mitochondria play an important role in cellular metabolism as they are responsible for producing the majority of cellular energy in the form of adenosine triphosphate. Mutations in mitochondrial genes responsible for the functioning of mitochondria can lead to various forms of mitochondrial diseases. These diseases may present with the following clinical symptoms: muscle weakness, movement disorders, neurological symptoms, impaired motility and absorption from the gastrointestinal tract. Diagnosis of mitochondrial diseases can be challenging due to genetic and clinical heterogeneity. Treatment currently remains a pressing problem, as research in this area is being actively conducted and new methods are emerging aimed at the therapy and treatment of these rare diseases.
About the Authors
O. I. Gumeniuk
Saratov State Medical University
Russian Federation
Russian Federation
I. A. Glushakov
St. Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Yu. V. Chernenkov
Saratov State Medical University
Russian Federation
Russian Federation
I. A. Bochkarev
Saratov State Medical University
Russian Federation
Russian Federation
G. V. Gafurova
Saratov State Medical University
Russian Federation
Russian Federation
E. E. Sukhushina
Saratov State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Gumeniuk O.I., Glushakov I.A., Chernenkov Yu.V., Bochkarev I.A., Gafurova G.V., Sukhushina E.E. Digestive system and mitochondrial diseases in children. Experimental and Clinical Gastroenterology. 2024;(6):43-46. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-226-6-43-46
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