Preview

Experimental and Clinical Gastroenterology

Advanced search

Difficulties in research and treatment of ulcerative colitis and Crohn’s disease

https://doi.org/10.31146/1682-8658-ecg-223-3-144-148

Abstract

Aim. To demonstrate the stages of development of the clinical picture, methods of diagnosis and treatment of Crohn’s disease during pregnancy, hepatocellular cancer and ulcerative colitis. The study uses clinical trial data and biomarkers, and explores new imaging techniques to develop more accurate approaches to diagnosis. Methods. A detailed analysis of several representative patients representing different aspects of the disease. Results. The first clinical case is a patient diagnosed with Crohn’s disease. The study provides data on primary symptoms such as abdominal pain, diarrhea, and weight loss. The course of the disease, the results of laboratory and instrumental studies are analyzed, and the effectiveness of the applied treatment methods is also highlighted. The second case is dedicated to a patient diagnosed with ulcerative colitis and hepatocellular cancer. In this context, the characteristic symptoms of ulcerative colitis are considered: abdominal pain, frequent changes in the type of stool and inflammatory changes in various parts of the intestine. The results of gastroscopy and colonoscopy are analyzed. The third clinical case is a combined diagnosis, when the patient simultaneously shows signs of ulcerative colitis and Crohn’s disease. This case highlights the complexity of differential diagnosis and the importance of an individualized approach to treatment. Conclusion. The research work devoted to the differential diagnosis and treatment of ulcerative colitis and Crohn’s disease has revealed several important aspects that doctors face in such clinical cases. These include: the complexity of differential diagnosis, the role of additional diagnostic methods, and an individualized approach to treatment.

About the Authors

S. N. Styazhkina
First Republican Clinical Hospital of the Ministry of Health of the Udmurt Republic; Izhevsk State Medical Academy
Russian Federation


M. N. Klimentov
First Republican Clinical Hospital of the Ministry of Health of the Udmurt Republic; Izhevsk State Medical Academy
Russian Federation


A. G. Bessonov
First Republican Clinical Hospital of the Ministry of Health of the Udmurt Republic
Russian Federation


K. R. Davletgaraeva
Izhevsk State Medical Academy
Russian Federation


E. E. Kuznetsov
Izhevsk State Medical Academy
Russian Federation


References

1. Ivashkin V.T. et al.; Russian Association of coloproctology completely, Russian Gastroenterological Association. [Crohn’s disease]. Clinical recommendations. Approved No: 176. Ministry of Health of the Russian Federation. 2020. 47 P. (in Russ.)@@ Ивашкин В. Т. и соавт. Клинические рекомендации. Болезнь Крона. Российская гастроэнтерологическая ассоциация, Ассоциация колопроктологов России. 2020. - 47с.

2. Stjazhkina S.N., Neganova O. A., Merzlyakova Yu.S., Hamadullin A. A. Current pregnancy during an ulcerous goal. Colloquium-journal. 2019;34 (10-3):54-55. (in Russ.)@@ Стяжкина С. Н., Неганова О. А., Мерзлякова Ю. С., Хамадуллин А. А. Течение беременности при язвенном колите. Colloquium-journal. 2019;34 (10-3):54-55.

3. Styazhkina S.N., Klimentov M. N., Neganova O. A., Abasova A. D., Bakirova L. R., Efremova D. S. Nonspecific ulcerative colitis and Crohn’s disease. Their differential diagnosis, morphological picture and analysis of prevalence among intestinal diseases. Capital of Science. 2020; 18 (1): 28-39. (in Russ.)@@ Стяжкина С. Н., Климентов М. Н., Неганова О. А., Абасова А. Д., Бакирова Л. Р., Ефремова Д. С. Неспецифический язвенный колит и болезнь Крона. Их дифференциальная диагностика, морфологическая картина и анализ распространнености среди заболеваний кишечника. Столица науки. 2020; 18 (1): 28-39.

4. Styazhkina S. N., Mullakhmetova A. A., Paderina A. S. Clinical case of diagnosis and treatment of Crohn’s disease. Diary of Science. 2020; 4 (40): 1-13. (in Russ.) (Available at: http://dnevniknauki.ru/images/publications/2020/4/medicine/Styazhkina_Mullahmetova_Paderina2.pdf Access: 05.05.2023.)@@ Стяжкина С. Н., Муллахметова А. А., Падерина А. С. Клинический случай диагностики и лечения болезни Крона. Дневник науки. 2020; 4 (40): 1-13. URL: http://dnevniknauki.ru/images/publications/2020/4/medicine/Styazhkina_Mullahmetova_Paderina2.pdf

5. Styazhkina S. N., Klimentov M. N., Chernyshova T. E., Neganova O. A., Subaev F. F., Matusevich A. E. Crohn’s disease in a patient with ciliopathy (cystic disease of the kidneys, liver, lungs), ankylosing spondylitis and secondary polyosteoarthritis, who is on programmed hemodialysis. Experimental and Clinical Gastroenterology. 2020;(9):85-88. (In Russ.) doi: 10.31146/1682-8658-ecg-181-9-85-88.@@ Стяжкина С. Н., Климентов М. Н., Чернышова Т. Е., Неганова О. А., Субаев Ф. Ф., Матусевич А. Е. Болезнь Крона у больного с цилиопатией (кистозная болезнь почек, печени, легких), анкилозирующим спондилитом и вторичным полиостеоартрозом, находящегося на программном гемодиализе. Экспериментальная и клиническая гастроэнтерология. 2020;(9):85-88. doi: 10.31146/1682-8658-ecg-181-9-85-88.

6. Klimentov M. N., Styazhkina S. N., Neganova O. A., Lyubimtseva M. S., Semibratova E. V., Turbin O. D. Crohn’s disease complications, requiring surgical treatment. Perm Medical Journal. 2019;36(3):98-105. (in Russ.) doi: 10.17816/pmj36398-105@@ Климентов М. Н., Стяжкина С. Н., Неганова О. А., Любимцева М. С., Семибратова Е. В., Турбин О. Д. Осложнения болезни Крона, требующие хирургической помощи. Пермский медицинский журнал. 2019;36(3):98-105. doi: 10.17816/pmj36398-105.


Review

For citations:


Styazhkina S.N., Klimentov M.N., Bessonov A.G., Davletgaraeva K.R., Kuznetsov E.E. Difficulties in research and treatment of ulcerative colitis and Crohn’s disease. Experimental and Clinical Gastroenterology. 2024;(3):144-148. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-223-3-144-148

Views: 118


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1682-8658 (Print)