20 years experience in diagnostics and treatment of the ektopated pancreas in the gastroduodenal zone in children
https://doi.org/10.31146/1682-8658-ecg-200-4-119-125
Abstract
Ectopia of the pancreas is a rare malformation that requires an individual approach to treatment. We present our experience in the diagnosis and treatment of 119 patients with EPI in the gastroduodenal zone. The main indication for surgical treatment is with a long-term intractable pain symptom. 28 (23.5%) patients were operated on, most of them from the laparoscopic approach. To determine the enzymatic activity of the gland, an assessment of the vegetative status was used. Vagotonia can be one of the causes of exocrine activity and hyperperistalsis of the stomach and duodenum. Among the operated patients, the parasympathetic type of autonomic nervous regulation was more common. Evaluation of the histostructure of the removed EPG macro- preparations indicated the predominance of type 3, indicating the presence of all components similar in structure to the tissue of a normal pancreas.
About the Authors
G. N. RumyantsevaRussian Federation
Galina N. Rumyantseva, MD; Professor; Head of the Department of Pediatric Surgery; pediatric surgeon
4, Sovetskaya St., Tver, 170100
E. I. Kazakova
Russian Federation
Elena I. Kazakova, postgraduate student of the Department of Pediatric Surgery; pediatric surgeon for emergency and emergency care for children of the Department of Purulent Surgery; endoscopist
4, Sovetskaya St., Tver, 170100
Yu. F. Brevdo
Russian Federation
Yuri F. Brevdo, pediatric surgeon; head of 1 surgical department
23, S. Razina str., 170100, Tver
T. N. Minko
Russian Federation
Tatiana N. Minko, Candidate of Medical Sciences; Head of the endoscopic department; endoscopist
23, S. Razina str., 170100, Tver
S. V. Trukhachev
Russian Federation
Sergey V. Trukhachev, Candidate of Medical Sciences; pediatric surgeon of the I surgical department
23, S. Razina str., 170100, Tver
V. V. Svetlov
Russian Federation
Vladislav V. Svetlov, Candidate of Medical Sciences; doctor of pediatric surgeon of the I surgical department
23, S. Razina str., 170100, Tver
A. N. Kazakov
Russian Federation
Alexander N. Kazakov, Candidate of Medical Sciences; pediatric surgeon of the Department of purulent surgery; ultrasound diagnostics doctor
23, S. Razina str., 170100, Tver
References
1. Lyalukova E.A., Anomalies of the pancreatoduodenal zone in patients with connective tissue dysplasia: clinical manifestations, patient management tactics. Siberian Medical Journal. 2011; 26 (3–2): 74–76. (in Russ.)
2. Dzhulay T.E., Aberrant pancreas in a patient with a dysplastic phenotype: a clinical case. Upper Volga Medical Journal. 2019; 18 (2): 51–54. (in Russ.)
3. Gokhale U.A., Nanda A., Pillai R., Al- Layla D. Heterotopic pancreas in the stomach: a case report and a brief review of the literature. JOP. 2010 May 5;11(3):255–7. PMID: 20442522.
4. Sander H.W., Hedley- Whyte E. T. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 6–2003. A nine-year-old girl with progressive weakness and are fl exia. N Engl J Med. 2003 Feb 20;348(8):735–43. doi: 10.1056/NEJMcpc020031. PMID: 12594319.
5. Yuan Z., Chen J., Zheng Q., Huang X. Y., Yang Z., Tang J. Heterotopic pancreas in the gastrointestinal tract. World J Gastroenterol. 2009;15(29):3701–3703. doi: 10.3748/wjg.15.3701
6. Seifarth F.G., Ryan M. L., Triana J., Knight C. G. Diagnosis and laparoscopic treatment of ileoileal intussusception secondary to heterotopic pancreas in an infant: case report and review of the literature. J Pediatr Surg. 2011 Feb;46(2): e33–6. doi: 10.1016/j.jpedsurg.2010.10.025. PMID: 21292068.
7. Monier A., Awad A., Szmigielski W., et al. Heterotopic pancreas: a rare cause of ileo-ileal intussusception. Pol J Radiol. 2014;79:349–351. Published 2014 Oct 4. doi: 10.12659/PJR.890913
8. Rao R.N., Kamlesh Y., Pallav G., Singla N. Ectopic pancreas presenting as periampullary tumor with obstructive jaundice and pruritus is a rare diagnostic and therapeutic dilemma. A case report. JOP. 2011 Nov 9;12(6):607–9. PMID: 22072252.
9. St Romain P., Muehlebach G., Damjanov I., Fan F. Adenocarcinoma arising in an ectopic mediastinal pancreas. Ann Diagn Pathol. 2012 Dec;16(6):494–7. Doi: 10.1016/j.anndiagpath.2011.04.005
10. Bente M. de Kok, Fleur I. de Korte, Lars E. Perk, Valeska Terpstra, J. Sven D. Mieog, Frank M. Zijta, «Acute Clinical Manifestation of Mesenteric Heterotopic Pancreatitis: A Pre- and Postoperative Confirmed Case», Case Reports in Gastrointestinal Medicine, vol. 2018, Article ID 5640379, 7 pages, 2018. doi: 10.1155/2018/5640379
11. Zhao Z., Sim C. K., Mantoo S. Heterotopic pancreas in the omphalomesenteric duct remnant in a 9-month-old girl: a case report and literature review. Diagn Pathol. 2017;12(1):49. Published 2017 Jul 5. doi: 10.1186/s13000–017–0643–2
12. Vasilev K. G., Stepanov A. E., Shumov N. D., et al. [Choristomas of the stomach in children]. Detskaia khirurgiia. 2004;3:16–9. (In Russ.)
13. Savina I.V., Lesko K. A., Bystrovskaya E. V. et al. Aberrant pancreas: diagnosis and therapeutic tactics. Clinical observation. Eff ective pharmacotherapy. 2020; 16 (30): 32–37. (in Russ.) doi: 10.33978/2307–3586–2020–16–30–32–37
14. Rumyantseva G. N., Kazakova E. I., Yusufov A. A., Brevdo Yu.F., Minko., Trukhachev S. V., et al. A rare case of successful treatment of double ectopia of the pancreas in the stomach wall in a child. Vopr. prakt. Pediatr. (Clinical Practice in Pediatrics). 2021; 16 (5): 141–146. (in Russ.) doi: 10.20953/1817–7646–2021–5–141–146
15. Vinokurova N.V., Tsap N. A., Druzhinina Yu.V., Valamina I.E, Ognev S. I. Clinical – endoscopic and morphological features of an ectopic pancreas in the stomach wall in children. Ural Medical Journal. 2012; 7 (99): 68–72. (in Russ.)
16. Vinokurova N. V. Diagnostics and surgical treatment of pancreatic ectopia in the stomach wall in children. Abstract of dissertation for the degree of candidate of medical sciences. Moscow. 2008. 23 P. (in Russ.)
Review
For citations:
Rumyantseva G.N., Kazakova E.I., Brevdo Yu.F., Minko T.N., Trukhachev S.V., Svetlov V.V., Kazakov A.N. 20 years experience in diagnostics and treatment of the ektopated pancreas in the gastroduodenal zone in children. Experimental and Clinical Gastroenterology. 2022;(4):119-125. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-200-4-119-125