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CLINICAL OBSERVATION OF EMERGENCY ENDOSCOPIC TREATMENT OF A PATIENT WITH STOMACH GASTROINTESTINAL STROMAL TUMORS COMPLICATED BY BLEEDING

Abstract

Gastrointestinal stromal tumors (GIST) are related to the group of rare gastrointestinal tract tumors with the mesenchymal origin and have their own morphological and immunnogical picture. The incidence of GIST is 10-20 observations per 1 000 000 population per year. About 5000-6000 new observations are recorded In the United States annually, 2000-2500 cases - in Russia. The average age among patients with GIST are primarily women 55-65 years old, rarely under the age of 40 years [2,3,4]. The most frequent GIST localization is 60-70 % in stomach and 25-35 % in small intestine [1,2]. Diagnosis of GIST includes a complex of Fibrogastroduodenoscopy, Ultrasonography and SKT examinations. Verification of GIST should be carried out under the results of the biopsy [4,5,7]. Treatment of patients with this type of disease involves a combination of surgery and chemotherapy.

About the Authors

L. V. Domarev
City Clinical Hospital named after S. I. Spasokukotsky Moscow Health Department
Russian Federation


K. A. Svitina
City Clinical Hospital named after S. I. Spasokukotsky Moscow Health Department
Russian Federation


E. A. Shitikov
City Clinical Hospital named after S. I. Spasokukotsky Moscow Health Department
Russian Federation


D. .. Kim
City Clinical Hospital named after S. I. Spasokukotsky Moscow Health Department
Russian Federation


O. I. Astakhova
City Clinical Hospital named after S. I. Spasokukotsky Moscow Health Department
Russian Federation


References

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2. Casali P. G., Blay J-Y., on behalf of the ESMO/CONTICANET/EUROBONET (2010). «Gastrointestinal stromal tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up». Annals of Oncology 21(suppl 5): v98-v102.

3. Demetri G., Benjamin R., Blanke C. D. et al. NCCN доклад: оптимальная терапия пациентов с гастроинтестинальными стромальными опухолями (GIST) - расширение и усовершенствование NCCN клинических рекомендаций // JNCCN. - 2004. - Vol. 2 (suppl. 1). - P. 1-26.

4. Dirnhofer S., Leyvraz S. Current standarts and progress in understanding and treatment of GIST. Swissmedkly 2009; 139 (7-8): 90-102.

5. Raut, Chandrajit and Dematteo, Ronald (March 2008). «Evidence-Guided Surgical Management of GIST: Beyond a Simple Case of Benign and Malignant». Ann. Surg. Onc. 15 (5): 1542.

6. Fletcher C. D., Berman J. J., Corless C. et al. Постановка диагноза гастроинтестинальных стромальных опухолей: общность подходов // Hum. Pathol. - 2002. - Vol. 33. - P. 459-465.

7. Heinrich M. C., Maki R. G., Corless C. L. et al. Primary Joensuu H. Гастроинтестинальные стромальные опухоли (GIST) // Ann. Oncol. - 2006. - Vol. 17 (suppl. 10). - Р. 280-286.

8. Miettinen M, Lasota J (2006). «Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis». Arch Pathol Lab Med 130 (10): 1466-78.


Review

For citations:


Domarev L.V., Svitina K.A., Shitikov E.A., Kim D..., Astakhova O.I. CLINICAL OBSERVATION OF EMERGENCY ENDOSCOPIC TREATMENT OF A PATIENT WITH STOMACH GASTROINTESTINAL STROMAL TUMORS COMPLICATED BY BLEEDING. Experimental and Clinical Gastroenterology. 2016;(4):98-100. (In Russ.)

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ISSN 1682-8658 (Print)