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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nogr-186</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>КЛИНИЧЕСКОЕ НАБЛЮДЕНИЕ ЭКСТРЕННОГО ЭНДОСКОПИЧЕСКОГО ЛЕЧЕНИЯ ПАЦИЕНТА С ГАСТРОИНТЕСТИНАЛЬНОЙ СТРОМАЛЬНОЙ ОПУХОЛЬЮ ЖЕЛУДКА, ОСЛОЖНЕННОЙ КРОВОТЕЧЕНИЕМ</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL OBSERVATION OF EMERGENCY ENDOSCOPIC TREATMENT OF A PATIENT WITH STOMACH GASTROINTESTINAL STROMAL TUMORS COMPLICATED BY BLEEDING</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Домарев</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Domarev</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Свитина</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Svitina</surname><given-names>K. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шитиков</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shitikov</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ким</surname><given-names>Д. ..</given-names></name><name name-style="western" xml:lang="en"><surname>Kim</surname><given-names>D. ..</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Астахова</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Astakhova</surname><given-names>O. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГКБ им. С. И. Спасокукоцкого ДЗ г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital named after S. I. Spasokukotsky Moscow Health Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>20</day><month>04</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>98</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Домарев Л.В., Свитина К.А., Шитиков Е.А., Ким Д..., Астахова О.И., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Домарев Л.В., Свитина К.А., Шитиков Е.А., Ким Д..., Астахова О.И.</copyright-holder><copyright-holder xml:lang="en">Domarev L.V., Svitina K.A., Shitikov E.A., Kim D..., Astakhova O.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/186">https://www.nogr.org/jour/article/view/186</self-uri><abstract><p>Гастроинтестинальные стромальные опухоли (ГИСО, GastroIntesinal Stromal Tumor - GIST в зарубежной литературе), относятся к группе редких опухолей желудочно-кишечного тракта мезенхимального происхождения с характерной морфологической и иммунногистохимической картиной. Частота встречаемости ГИСО составляет 10-20 наблюдений на 1 000 000 населения в год. В США ежегодно регистрируется около 5000-6000 новых наблюдений, в России - 2000-2500 заболевших. Возрастная категория пациентов с ГИСО, в основном женщины 55-65 лет, редко лица моложе 40 лет [2,3,4]. Большинство GIST классифицируют как веретеноклеточные (70%), эпителиоидные (20%) и смешанные (10%). Наиболее частой локализацией GIST является желудок 60-70% и тонкая кишка 25-35% [1,2]. Диагностика ГИСО включает в себя комплекс эндоскопических (ЭГДС, ЭНДО-УЗИ) и лучевых (СКТ) методов исследования. Верификация ГИСО должна проводиться по результатам биопсии (иммунногистохимия) патоморфологом [4,5,7]. Лечение пациентов с данным видом патологии предполагает сочетание хирургического вмешательства и химиотерапии.</p></abstract><trans-abstract xml:lang="en"><p>Gastrointestinal stromal tumors (GIST) are related to the group of rare gastrointestinal tract tumors with the mesenchymal origin and have their own morphological and immunnogical picture. The incidence of GIST is 10-20 observations per 1 000 000 population per year. About 5000-6000 new observations are recorded In the United States annually, 2000-2500 cases - in Russia. The average age among patients with GIST are primarily women 55-65 years old, rarely under the age of 40 years [2,3,4]. The most frequent GIST localization is 60-70 % in stomach and 25-35 % in small intestine [1,2]. Diagnosis of GIST includes a complex of Fibrogastroduodenoscopy, Ultrasonography and SKT examinations. Verification of GIST should be carried out under the results of the biopsy [4,5,7]. Treatment of patients with this type of disease involves a combination of surgery and chemotherapy.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cassier P. A., Dufresne A., Blay J. Y. Controversies in the Adjuvant Treatment of Gastrointestinal Stromal Tumors (GIST) with Imatinib ASCO Educational Book; 2008.</mixed-citation><mixed-citation xml:lang="en">Cassier P. A., Dufresne A., Blay J. Y. Controversies in the Adjuvant Treatment of Gastrointestinal Stromal Tumors (GIST) with Imatinib ASCO Educational Book; 2008.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Casali P. G., Blay J-Y., on behalf of the ESMO/CONTICANET/EUROBONET (2010). «Gastrointestinal stromal tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up». 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Arch Pathol Lab Med 130 (10): 1466-78.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
