Crown disease with extrainterinal manifestations in the form of granulematous alveolitis
https://doi.org/10.31146/1682-8658-ecg-195-11-90-96
Abstract
Objective: To present a clinical description of the observation of a patient with Crohn’s disease (CD) with extraintestinal manifestations in the form of granulomatous alveolitis.
Materials and Methods: A brief review of the literature on the current understanding of the prevalence and clinical manifestations of lung lesions in inflammatory bowel diseases (IBD) and CD, as well as a description of a patient with this pathology with the results of autopsy is presented.
Results: The rare presence of granulomatous lung lesions in a patient with CD was proved.
Conclusion: Difficulties in the differential diagnosis and treatment of CD lung lesions are shown. In particular, suspicion of tuberculous lesion, lung abscess creates potential risks of generalization of the process when using such therapeutic effects as glucocorticosteroids, cytostatics, immunosuppressants, biological genetically engineered drugs and active surgical intervention. The authors hope that the described observation will alert doctors in terms of possible systemic pulmonary lesions in CD.
Supporting agencies: The authors express their gratitude for their grate help in writing the article: the pathologist doctor of the Perm Clinical Pathoanatomical Bureau Ashirov Damir Danilovich for providing and evaluating the results of the pathological and histological preparations; Head of the Department of Educational, Methodological and Scientific Support of the Perm State Medical University named by academician E. A. Wagner, Candidate of Biological Sciences Natalia Vadimovna Chemurzieva for preparing microphotographs of histological preparations; head of the X-ray department of Perm Clinical Medical Unit № 1 Elena Victorovna Lonskaya for providing and interpreting computer tomography scan data.
About the Authors
P. N. Barlamov
Perm State Medical University named after academician E. Wagner
Russian Federation
Russian Federation
Pavel N. Barlamov, Dr. Med. Sciences, associate professor, professor of the department of outpatient therapy
614990, Perm
Yu. I. Tretyakova
Perm State Medical University named after academician E. Wagner
Russian Federation
Russian Federation
Yuliya I. Tretyakova, Candidate of Medical Sciences, Associate Professor of the Department of Polyclinic Therapy
614990, Perm
V. G. Zhelobov
Perm State Medical University named after academician E. Wagner
Russian Federation
Russian Federation
Vladimir G. Zhelobov, Dr. Med. Sciences, associate professor
614990, Perm
O. V. Khlynova
Perm State Medical University named after academician E. Wagner
Russian Federation
Russian Federation
Olga V. Khlynova, Dr. Med. Sciences, Professor, Corresponding Member RAS. head Department of Hospital Therapy and Cardiology
614990, Perm
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Review
For citations:
Barlamov P.N., Tretyakova Yu.I., Zhelobov V.G., Khlynova O.V. Crown disease with extrainterinal manifestations in the form of granulematous alveolitis. Experimental and Clinical Gastroenterology. 2021;(11):90-96. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-195-11-90-96
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