Preview

Экспериментальная и клиническая гастроэнтерология

Расширенный поиск

Материалы конференции Gastro Update Eвропа 2020, 4-5 сентября 2020 г

https://doi.org/10.31146/1682-8658-ecg-186-2-120-134

Полный текст:

Аннотация

В данном обзоре в повествовательной форме кратко изложены клинически важные передовые исследования представленные для обсуждения на конференции Gastro Update Europe 2020. По мнению выдающихся лекторов данная информация является жизненно необходимой в практике клинициста в области диагностики и лечения желудочно-кишечных заболеваний. Для повышения образовательной ценности, краткое резюме докладов сопровождается личными пояснениями автора обзора. Учитывая повествовательный характер обзора, выводы и заключения в значительной степени основаны на мнениях экспертов, а ссылки в настоящем резюме ограничиваются включенными слайд-изображениями.

Об авторе

Гвидо Титгат
Академический медицинский центр Медицинского унивирситета Амстердама
Нидерланды


Список литературы

1. GBD 2017 Gastro-oesophageal Reflux Disease Collaborators. Lancet Gastroenterol Hepatol 2020 Jun;5(6):561-58 https://doi.org/10.1016/S2468-1253

2. Kim et al. Gut Liver. 2019 Nov 15;13(6):642-648

3. Xiao et al. Gut 2020;69:224-230

4. Thélin CS et al. Aliment Pharmacol Ther. 2020;51:421-434

5. Cheng Mei Li et al. Aliment Pharmacol Ther. 2020;51:410-420

6. Delshad SD et al. Gastroenterology. 2020;158(5):1250-1261

7. Fass R et al. Gastroenterology. 2020;158(8):2286-2293. doi:10.1053/j.gastro.2020.01.034

8. Naik RD et al. Curr Treat Options Gastroenterol. 2019;17(1):1-17

9. Patel DA et al. Gastroenterology. 2019;156(6):1617-1626

10. Zerbib et al. Aliment Pharmacol Ther. 2020;52:637-645

11. Vaezi MF et al. Gastroenterology. 2020;158(8):2093-2103

12. Akiyama et al. Digestion. 2020;101(2):174-183. doi:10.1159/000497775

13. Spechler SJ et al. N Engl J Med. 2019;381(16):1513-1523

14. Jankowski et al. Lancet 2018; 392(10145): 400-408

15. Shaheen et al, Am J Gastroenterol 2016; 111:30-50

16. Weusten et al. Endoscopy. 2017 Feb;49(2):191-198

17. Tan MC et al. Aliment Pharmacol Ther. 2020;52(1):20-36

18. Rubenstein JH et al. Gastroenterology. 2020;158(8):2082-2092. doi:10.1053/j.gastro.2020.02.037

19. Fitzgerald RC et al. Lancet. 2020;396(10247):333-344

20. Adapted Malfertheiner et al. Nat Rev Gastroenterol and Hepatol 2017;14(12):697-710

21. Brusselaers et al. J Gastroenterol. 2020;55(4):453-461

22. Almario et al. American Journal of Gastroenterology (pre-print posted online July 7, 2020)

23. Lee SW et al. Gut 2020 Jul 30; gutjnl-2020-322248

24. Dellon et al. Gastroenterology 2018; 155: 1022-1033

25. Rokkas T et al. J Clin Gastroenterol. [published online ahead of print, 2020 May 8

26. O’Shea KM et al. Gastroenterology. 2018 Jan;154(2):333-345

27. Hirano I et al. Gastroenterology 2019;156:592-603

28. Dellon ES et al. Clin Gastroenterol Hepatol. 2020; S1542-3565(20)303487.doi:10.1016/j.cgh.2020.03.036

29. Dellon ES et al.Gastroenterology. 2019;157(1):65-73

30. Hirano I et al.Gastroenterology. 2020;158(1):111-122

31. Abraham NS et al. [published online ahead of print, 2020 Jul 13]. Aliment Pharmacol Ther. 2020;10.1111/apt.15790

32. Malfertheiner et al. Curr Treat Options Gastroenterol. 2018 Dec;16(4):605-615

33. Doorakkers et al. Gut. 2018 Dec;67(12):2092-2096

34. Choi IJ, Kim CG, Lee JY, et al. N Engl J Med. 2020;382(5):427-436

35. Kumar S et al. Gastroenterology. 2020;158(3):527-536.e7. doi:10.1053/j.gastro.2019.10.019

36. Chiang TH et al. [published online ahead of print, 2020 Aug 13]. Gut. 2020; gutjnl-2020-322200. doi:10.1136/gutjnl-2020-322200

37. Beresniak A et al. Helicobacter. 2020;25(4): e12693.

38. Chen Q et al. Aliment Pharmacol Ther. 2019;49(11):1385-1394

39. Fallone CA et al. Gastroenterology. 2019;157(1):44-53

40. Graham et al. Ann Intern Med. 5 May 2020 doi:10.7326/M19-3734

41. Saracino IM et al. Eur J Intern Med. 2020; S0953-6205(20)30275

42. Suzuki S et al. Gut. 2020;69(6):1019-1026

43. Liou JM et al. Lancet Infect Dis. 2019;19(10):1109-1120.

44. McFarland LV Dig Dis Sci. 2020;10.1007/s10620-020-06244-z. doi:10.1007/s10620-020-06244published online ahead of print, 2020 Apr

45. Cárdenas PA et al. Eur J Clin Microbiol Infect Dis. 2020;39(7):1365-1372

46. Rubin JE, Crowe SE. Celiac Disease. Ann Intern Med. 2020;172(1): ITC1-ITC16.

47. Uhde M, Caio G, De Giorgio R, Green PH, Volta U, Alaedini A. Subclass Profile of IgG Antibody Response to Gluten Differentiates Non-Celiac Gluten Sensitivity from Celiac Disease [published online ahead of print, 2020 Jul 20]. Gastroenterology. 2020; S0016-5085(20)34992-1.

48. Airaksinen L, Myllymäki L, Kaukinen K, et al. Differences Between Familial and Sporadic Celiac Disease [published online ahead of print, 2020 Jul 23]. Dig Dis Sci. 2020;10.1007/s10620-020-06490-1

49. Huang X, Schuppan D, Rojas Tovar LE, Zevallos VF, Loponen J, Gänzle M. Sourdough Fermentation Degrades Wheat Alpha-Amylase/Trypsin Inhibitor (ATI) and Reduces Pro- Inflammatory Activity. Foods. 2020;9(7): E943. Published 2020 Jul 16. doi:10.3390/foods9070943

50. Caio G, Lungaro L, Segata N, et al. Effect of Gluten-Free Diet on Gut Microbiota Composition in Patients with Celiac Disease and Non-Celiac Gluten/Wheat Sensitivity. Nutrients. 2020;12(6):1832.

51. Koskinen I, Virta LJ, Huhtala H, Ilus T, Kaukinen K, Collin P. Overall and Cause-Specific Mortality in Adult Celiac Disease and Dermatitis Herpetiformis Diagnosed in the 21st Century. Am J Gastroenterol. 2020;115(7):1117-1124.

52. Lebwohl B, Green PHR, Söderling J, Roelstraete B, Ludvigsson JF. Association Between Celiac Disease and Mortality Risk in a Swedish Population. JAMA. 2020;323(13):1277-1285.

53. Kårhus LL, Skaaby T, Petersen J, et al. Long-term Consequences of Undiagnosed Celiac Seropositivity [published online ahead of print, 2020 Jun 16]. Am J Gastroenterol. 2020;10.14309/ajg.0000000000000737.

54. Silvester JA, Comino I, Kelly CP, Sousa C, Duerksen DR; DOGGIE BAG Study Group. Most Patients With Celiac Disease on Gluten-Free Diets Consume Measurable Amounts of Gluten. Gastroenterology. 2020;158(5):1497-1499.e1

55. Elli L, Bascuñán K, di Lernia L, et al. Safety of occasional ingestion of gluten in patients with celiac disease: a real-life study. BMC Med. 2020;18(1):42.

56. Pinto-Sanchez MI, Seiler CL, Santesso N, et al. Association Between Inflammatory Bowel Diseases and Celiac Disease: A Systematic Review and Meta-Analysis Gastroenterology. 2020; S0016-5085(20)30609-0.

57. Andersen V, Möller S, Jensen PB, Møller FT, Green A. Caesarean Delivery and Risk of Chronic Inflammatory Diseases (Inflammatory Bowel Disease, Rheumatoid Arthritis, Coeliac Disease, and Diabetes Mellitus): A Population Based Registry Study of 2,699,479 Births in Denmark During 1973-2016. Clin Epidemiol. 2020;12:287-293.

58. Croall ID, Sanders DS, Hadjivassiliou M, Hoggard N. Cognitive Deficit and White Matter Changes in Persons With Celiac Disease: A Population-Based Study. Gastroenterology. 2020;158(8):2112-2122.

59. Caio G, Ciccocioppo R, Zoli G, De Giorgio R, Volta U. Therapeutic options for coeliac disease: What else beyond gluten-free diet?. Dig Liver Dis. 2020;52(2):130-137.

60. Freitag TL, Podojil JR, Pearson RM, et al. Gliadin Nanoparticles Induce Immune Tolerance to Gliadin in Mouse Models of Celiac Disease. Gastroenterology. 2020;158(6):1667-1681.e12.

61. Andrén Aronsson C, Lee HS, Hård Af Segerstad EM, et al. Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk. JAMA. 2019;322(6):514-523. doi:10.1001/jama.2019.10329

62. Scaldaferri F, Ianiro G, Privitera G, et al. The Thrilling Journey of SARS-CoV-2 into the Intestine: From Pathogenesis to Future Clinical Implications [published online ahead of print, 2020 Jul 28]. Inflamm Bowel Dis. 2020; izaa181. doi:10.1093/ibd/izaa181

63. Shi Z, Zou J, Zhang Z, et al. Segmented Filamentous Bacteria Prevent and Cure Rotavirus Infection. Cell. 2019;179(3):644-658.

64. Andreyev HJN, Lalji A, Mohammed K, et al. The FOCCUS study: a prospective evaluation of the frequency, severity and treatable causes of gastrointestinal symptoms during and after chemotherapy [published online ahead of print, 2020 Jul 16]. Support Care Cancer. 2020;10.1007/s00520-020-05610-x.

65. Kim BT, Kim KM, Kim KN. The Effect of Ursodeoxycholic Acid on Small Intestinal Bacterial Overgrowth in Patients with Functional Dyspepsia: A Pilot Randomized Controlled Trial. Nutrients. 2020;12(5):1410

66. Mouillot T, Rhyman N, Gauthier C, et al. Study of Small Intestinal Bacterial Overgrowth in a Cohort of Patients with Abdominal Symptoms Who Underwent Bariatric Surgery. Obes Surg. 2020;30(6):2331-2337.

67. Nielsen HL, Dalager-Pedersen M, Nielsen H. High risk of microscopic colitis after Campylobacter concisus infection: population-based cohort study [published online ahead of print, 2020 Feb 28]. Gut. 2020; gutjnl-2019-319771. doi:10.1136/gutjnl-2019-319771

68. Babar S, El Kurdi B, El Iskandarani M, et al. Oral vancomycin prophylaxis for the prevention of Clostridium difficile infection: A systematic review and meta-analysis [published online ahead of print, 2020 Jun 29]. Infect Control Hosp Epidemiol. 2020;1-8.

69. Wombwell E, Patterson ME, Bransteitter B, Gillen LR. The effect of Saccharomyces boulardii primary prevention on risk of Hospital Onset Clostridioides difficile infection in hospitalized patients administered antibiotics frequently associated with Clostridioides difficile infection [published online ahead of print, 2020 Jun 23]. Clin Infect Dis. 2020; ciaa808.

70. Kitchin N, Remich SA, Peterson J, et al. A Phase 2 Study Evaluating the Safety, Tolerability, and Immunogenicity of Two 3-Dose Regimens of a Clostridium difficile Vaccine in Healthy US Adults Aged 65 to 85 Years. Clin Infect Dis. 2020;70(1):1-10.

71. Khanna S, Pardi D. Fecal Microbiota Transplantation for Recurrent Clostridioides difficile infection: The COVID-19 Era. Am J Gastroenterol. 2020;115(7):971-974.

72. Connor BA, Martin GJ, Riddle MS. Use of the Multiplex Diagnostic PCR Panel in Diarrheal Disease: Expert Guidance on the Interpretation of Results With a Focus on Travelers’ Diarrhea [published online ahead of print, 2020 Jun 16]. Am J Gastroenterol. 2020;10.14309

73. Schaumburg F, Correa-Martinez CL, Niemann S, Köck R, Becker K. Aetiology of traveller’s diarrhea: A nested case-control study [published online ahead of print, 2020 Apr 25]. Travel Med Infect Dis. 2020;101696.

74. Boxall MD, Day MR, Greig DR, Jenkins C. Antimicrobial resistance profiles of diarrhoeagenic Escherichia coli isolated from travellers returning to the UK, 2015-2017 [published online ahead of print, 2020 Jun 12]. J Med Microbiol. 2020;10.1099/jmm.0.001214. doi:10.1099/jmm.0.001214

75. Furuya-Kanamori L, Stone J, Yakob L, et al. Risk factors for acquisition of multidrug- resistant Enterobacterales among international travellers: a synthesis of cumulative evidence. J Travel Med. 2020;27(1): taz083.

76. Halmos EP, Mack A, Gibson PR. Review article: emulsifiers in the food supply and implications for gastrointestinal disease. Aliment Pharmacol Ther. 2019;49(1):41-50.

77. Peters RJB, Oomen AG, van Bemmel G, et al. Silicon dioxide and titanium dioxide particles found in human tissues. Nanotoxicology. 2020;14(3):420-432. doi:10.1080/17435390.2020.1718232

78. Talamini L, Gimondi S, Violatto MB, et al. Repeated administration of the food additive E171 to mice results in accumulation in intestine and liver and promotes an inflammatory status. Nanotoxicology. 2019;13(8):1087-1101.

79. Stoffel EM et al., Gastroenterology, 2020, 158: 341

80. Jeon J et al., Gastroenterology, 2018, 154: 2152

81. Robertson DJ et al., Gastroenterology, 219, 156: 904

82. Zhang J et al., Gut, 2019, 68: 1971

83. Echle A et al., Gastroenterology 2020, June 17

84. Pilonis ND et al., Annals Intern Med, 2020, 173: 81

85. Lieberman A et al., Cancer Epidemiol Biomarkers Prev 2019, 28: 1902

86. Helsingen L et al., BMJ, 2019, 367: l5515

87. Zorzi M et al., J Med Screen, 2020, May 11

88. Terlouw LG, UEG Journal 2020, 8: 371

89. Parasa et al., Gut. 2019 Dec;68(12):2122-2128

90. Wani et al., Am J Gastroenterol. 2019 Aug;114(8):1256-1264

91. ESGE Position Statement; Weusten et al, Endoscopy 2017 Feb;49(2):191-198

92. Minashi et al., Gastroenterology. 2019 157:382-390

93. https://www.researchgate.net/profile/Uchenna_Odi2/publication/326834670/figure/fig 8/AS:656388581756929@1533506641355/Difference-between-traditional-machine-learning-and-deep-learning-Alex-2017_W640.jpg

94. https://www.digitaltrends.com/cool-tech/what-is-an-artificial-neural-network

95. Fons van der Sommen et al., Gut, 2020 May 11; gutjnl-2019-320466, (online ahead of print)

96. Van Rijn, Am J Gastroenterol 2006 Feb;101(2):343-50

97. Visrodia et al, Gastroenterology 2016 Mar;150(3):599-607.e7

98. Pimenta-Melo et al, Eur J Gastroenterol Hepatol 2016 Sep;28(9):1041-9

99. Luo et al., Lancet Oncology, 2019, Dec;20(12):1645-1654

100. Nakagawa et al., Gastrointestinal Endoscopy, 2019 Sep;90(3):407-414

101. Wu L et al., Gut. 2019 Dec;68(12):2161-2169

102. Bisschops et al, Endoscopy 2016 Sep;48(9):843-64

103. Harvey PR et al., GUT 2019 Jul;68(7):1146-1151

104. Uemura KL et al., Endosc Int Open. 2020 Jul;8(7): E911-E923

105. Careyva B et al., Am Fam Physician. 2016 Dec 15;94(12):980-986

106. Ibrahim M et al., Gut. 2019;68:844-853

107. Radaeli F et al., Gut. 2019 Jun;68(6):969-976

108. Veitch AM et al, ESGE Guidelines. Endoscopy 2016; 48: 1-18

109. Van Baar ACG et al., Gut. 2020 69:295-303 22. Peters Y et al., Gut. 2020 Jul;69(7):1169-1172

110. Pekgoz M. World J Gastroenterol 2019; 25: 4019-42

111. Elzmunzer et al. N Engl J Med 2012; 366: 1414-22

112. Fogel et al. Lancet Gastroenterol Hepatol 2020; 5: 132-41

113. Dumonceau et al. Endoscopy 2014; 46: 799-15

114. Navaneethan et al. Gastrointest Endosc 2015; 81: 168-76

115. Dorrell et al. Diagnostics 2020, 10, 337

116. Singhi et al. Gut 2020: 69: 52-61

117. Arvanitakis et al. Endoscopy 2018; 50: 524-46

118. Working Group IAP/APA Acute Pancreatitis Guidelines. Pancreatology 2013; 13: e1-15

119. Crockett et al. Gastroenterology 2018; 154: 1096-101

120. Schepers et al, Bruno. Lancet 2020; 396: 167-76

121. Okamoto et al. Tokyo guidelines for the management of acute cholecystitis. J Hepatobiliary Pancreat Sci 2018;25:55-72

122. Teoh et al. Endoscopy 2017; 49: 130-8

123. Dollhopf et al. Gastrointest Endosc 2017; 86: 636-43

124. Teoh et al. Gut 2020; 69: 1085-91

125. McCarty et al. Endosc Ultrasound 2020; 9: 6-15

126. Robles-Medrandra et al. Endoscopy 2020; 52: 268-75

127. He X, Hang D et al., Gastroenterology, 2020, volume: 158 page 852-861

128. Lee JK et al., Gastroenterology, 2020, volume: 158 page 884-894

129. Wieszczy P et al., Gastroenterology, 2020, volume: 158 page 875-883

130. Klein A, Tate DJ et al., Gastroenterology, 2019, volume: 156 page 604-613

131. Cross A, et al. Gut 2020, volume 69 page 1645-1658

132. Pohl H et al., Gastroenterology, 2020, volume: 159 page 119-128

133. Pohl H et al., Gastroenterology, 2019, volume: 157 page 977-984

134. Feagins LA et al., Gastroenterology, 2019, volume: 157 page 967-976

135. Albeniz E et al., Gastroenterology, 2019, volume: 157 page 1213-1221

136. Spadaccini M et al., Gastroenterology, 2020, volume: 159 page 148-1258

137. Takeuchi Y et al., Ann Intern Med, 2019, volume: 171 page 229-237

138. Zwager LW et al., Endoscopy, 2020, Jun 4. doi: 10.1055/a-1176-1107

139. Wang P, et et al., Lancet Gastroentero Hep, 2020, 5:343-351

140. Gong D, et et al., Lancet Gastroentero Hep, 2020, 5:352-361

141. Repici A, et et al., Gastroenterology, 2020, S0016-5085(20)30583-7

142. Hassan C, et al., Gastrointest Endosc, 2020 Jun 26: S0016-5107(20)34523-5

143. Su, et et al., Gastrointest Endosc, 2020, 91:415

144. Bretthauer M, Kaminski MF, et al., JAMA Intern Med., 2016 Jul 1;176(7):894-902

145. Niikura R, et al., Gastroenterology, 2020, 158:168-175

146. Kherad O, et al., Aliment Pharmacol Ther, 2020, 00:1-15

147. Dobszai D et al, World J Gastroenterol 2019;25:729-43

148. Miko A et al, Pancreas 2018;47:917-23

149. Krishna SG et al. Pancreas 2018;47:996-1002

150. Jones JD et al. Pancreas 2018;47:1317-1321

151. Hollemans RA, et al. Gastroenterology 2019;156:1016-26

152. Van Santvoort HC et al. NEJM 2010;362:1491

153. Bang JY et al. Gastroenterology 2019;156:1027-1040

154. Kamal A et al. Am J Gastroenterol 2019;114:339-347

155. Luo H et al. Clin Gastroenterol Hepatol 2019;17:1597-1606

156. Olesen SS et al, Am J Gastroenterol 2019;114:656-64

157. Majumder S et al, Clin Gastroenterol Hepatol 2018;16:1947-53

158. Hart PA et al, Gut 2013;62:1607-15

159. Collaborators, Gut 2018;67:789-804

160. Okazaki K et al, Am J Gastroenterol 2018;113:1412-6

161. Tavakkoli A et al, CGH 2020;18:171-8

162. Beatty G et al, ASCO 2017

163. Paiella S et al, Am J Gastroenterol 2019;114:665-70

164. Henrikson NB et al, Jama 2019;322:445-54

165. Owens DK et al, Jama 2019;322:438-44

166. Goggins M, et al, Gut 2020;69:7-17

167. Corral JE et al, Clin Gastroent Hepat 2019;17:41-53

168. Amodio A, et al, Pancreas 2019;48:544-7

169. Vanella et al, Pancreatology 2019;19:237-44

170. Sharma A et al, Gastroenterology 2018;155:490-500

171. Sah RP et al, Gastroenterology 2019;156:1742-52

172. Mueller AM et al, Pancreas 2018;47:807-15

173. Delshad et al., Gastroenterology 2020; 158: 1250-61

174. Karamanolis et al., Dig Dis Sci 2008; 53: 2387-93

175. Vaezi et al., Gastroenterology 2020; 158: 2093-103

176. Boeckxstaens et al., Lancet 2014; 383: 83-93

177. Sediqi et al., Surgical Endoscopy, early online 4/2020

178. Werner et al., NEJM 2019; 381; 2219-29

179. Stanghellini et al., Gastroenterology 2016; 150: 1380-92

180. Masuy et al., APT 2019; 49: 1134-72

181. Pittayanon et al., Am J Gastro 2019; 114: 233-243

182. Chey et al., Clin Transl Gastro 2019; 10(4)

183. Janssen et al., Am. J. Gastroenterol. 2013; 108(9):1382-91

184. Vijayvargiya et al., Gastroenterology. 2019; 156: 1650-60

185. Carbone et al., Am J Gastroenterol 2019; 114: 1265-74

186. Ducrotté et al., Gastroenterology 2020; 158: 506-14

187. Carlin et al., Gastroenterology; early online 7/2020

188. Pasricha et al., Gastroenterology. 2018; 154: 65-76

189. Moayyedi et al., UEG Journal 2017; 5: 773-88

190. Weerts et al., Gastroenterology 2020; 158: 123-36

191. Plasse et al., Am. J. Gastroenterol. 2020 Jun 24; online ahead of print

192. Dionne et al., Am. J. Gastroenterol. 2018; 113: 1290-1300

193. Barbara et al., Gastroenterology 2004; 126: 693-702

194. Fritscher-Ravens et al., Gastroenterology 2019; 157: 109-18 https://www.youtube.com/watch?v=Dim7YXYlRm0

195. Xu et al., Am. J. Gastroenterol 2019; 114: 1043-50 25. Lahtinen et al., APT 2020; 51; 1321-31

196. Holvoet et al., Gastroenterology 2020 Jul 15; S0016-5085(20)34937-4. Online ahead of print.

197. El-Salhy et al., Gut 2020; 69: 857-67


Для цитирования:


Титгат Г. Материалы конференции Gastro Update Eвропа 2020, 4-5 сентября 2020 г. Экспериментальная и клиническая гастроэнтерология. 2021;(2):120-134. https://doi.org/10.31146/1682-8658-ecg-186-2-120-134

For citation:


Tytgat N.J. Meeting report of Gastro Update Europe 2020, September 4-5, 2020. Experimental and Clinical Gastroenterology. 2021;(2):120-134. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-186-2-120-134

Просмотров: 504


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 1682-8658 (Print)