Some mechanisms of osteopenia in chronic pancreatitis
Abstract
Purpose of the study. To investigate the frequency and some mechanisms of osteopenia in chronic pancreatitis. Materials and methods. In a study of 161 patients with chronic pancreatitis included. Bone-turnover markers was measured: osteocalcin, β-CrossLaps, dual-energy X-ray absorptiometry was performed. The analysis of the content cytokines IL-2, IL-6, IL-8 in colonic biopsies, composition of the gut microbiota. Results. Bone disorders is associated with an increase in cytokines in colon biopsy and the altered intestinal microbiota.
About the Authors
A. P. Bykova
Saratov State Medical University n. a. V. I. Razumovsky
Russian Federation
Russian Federation
I. V. Kozlova
Saratov State Medical University n. a. V. I. Razumovsky
Russian Federation
Russian Federation
E. E. Tsareva
Orthopedics and Neurosurgery of Saratov State Medical University n. a. V. I. Razumovsky
Russian Federation
Russian Federation
Review
For citations:
Bykova A.P., Kozlova I.V., Tsareva E.E. Some mechanisms of osteopenia in chronic pancreatitis. Experimental and Clinical Gastroenterology. 2018;(7):112-117. (In Russ.)
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