Prevalence of helicobacter pylori in population-based studies in Novosibirsk (1994-2015)

Abstract

Aim. To study 20-year trends in the prevalence of antibodies to Helicobacter pylori and CagA antigen in the Novosibirsk population. Methods. Within the framework of population-based studies over 1994-2015 random representative samples of adolescents and adults aged 25-69 years of both sexes including 1,438 citizens (754 adults and 684 schoolchildren) were studied. Results. In adults, the infection rates of Helicobacter pylori did not change significantly. In adolescents, the prevalence slightly decreased, but the dynamics of decline were much less pronounced than in Eastern and, especially, Western Europe. Cytotoxic strains (CagA) were identified approximately at the same frequency during this time. Conclusion. Interventions are needed to improve the sanitary and hygienic control of the quality of food and water.