Acute drug poisoning during adolescence

Abstract

The aim to study the structure and characteristics of clinical and laboratory manifestations of acute drug poisoning (DP) among adolescent children. Materials and methods: 177 children were admitted to the Department of Toxicology N. F. Filatov Children’s City Clinical Hospital № 13 in the period from 2016 to 2018 with acute poisoning of drug poisoning. The diagnosis was confirmed by chemical-toxicological examination of urine by thin layer chromatography. The features of clinical manifestations and laboratory studies in patients with acute drug poisoning have been studied. Results: From 2016 to 2018, the number of acute DP among adolescents in Moscow increased 7 times, with a predominance of males (71%). Plant or synthetic cannabinoids, as well as lysergic acid derivatives (LSD), occupy a leading position in the choice of DP. In 39% of patients reported severe severity of poisoning. All patients had damage to the central nervous system (CNS) in the form of depression or arousal syndrome, the majority - disorders of the cardiovascular system, respiratory organs, liver and kidneys. As a result of acute toxic damage to the DP in patients already after 24 hours from the onset of the disease, changes in laboratory parameters in the form of cytolysis syndrome, hypocholesterolemia, lactic acidosis were noted.