Effect of bone marrow allotransplantation on neurally mediated appendix vermiformis cells

Abstract

Luminescent and immunohistochemical changes in various morpho-functional areas of appendix vermiformis after bone marrow allotransplantation in animals are described. The obtained data indicate an increase in mast and granular luminescent cells with an increased content of biogenic amines in them in 40 minutes after transplantation. In the germinal centre of lymphoid nodes in appendix vermiformis cellular programmed differentiations with a high content of catecholamines and serotonin were defined. An active proliferative cellular activity both in lamina propria in crypts’ t. mucosa and in lymphoid nodules of appendix vermiformis was identified. In 2 hours in experimental animals the number of MCs and GLCs decreased both in t. mucosa and in t. s/mucosa appendix vermiformis and the content of catecholamines and serotonin in them decreased, which resulted in a decrease in proliferative cellular activity.