Monitoring of a clinical and endoscopic picture of patients with the stable stenocardia associated with a gastroesophageal reflux disease

Aim. To estimate a clinical endoscopic picture in patients with the stable stenocardia associated with a gastroesophageal reflux disease (GERD). Material and methods of research. In the course of the research two groups of patients with stable stenocardia have been consistently created. The I group included the patients with a concomitant GERD (n=28), the II group - with a concomitant chronic gastritis (n=35). Infection H. pylori was confirmed for all patients. Patients of both groups received eradication therapy together with the basic therapy. The duration of the observation was 24 weeks. The dynamics of a clinical endoscopic picture has been estimated. Results. At patients of the I group the clinical status in addition to anginous pains was characterized by the expressed dyspeptic symptoms having negative impact on the quality of life of patients. Monitoring of an endoscopic picture of a gastroduodenal zone after eradikation of H. pylori showed improvement at sick patients of both groups. However more significant improvement of clinical parameters and indicators of quality of life is noted at patients with the stable stenocardia associated with GERD (the I group). Conclusion. Inclusion in an algorithm of treatment of patients with stable stenocardia with a combination of GERD of eradication therapy of H. pylori promotes stabilization of a clinical endoscopic picture, provides a reduction of dyspeptic symptoms, improves the quality of life, raises a self-assessment of state by the patients.

стабильная стенокардия, гастроэзофагеальная рефлюксная болезнь, Нelicobacter pylori, эндоскопические изменения, stable stenocardia, gastroesophageal reflux disease, Helicobacter pylori, endoscopic changes