Asynchronous quantitative computed tomography (QCT) in assessing the impact of the upper gastrointestinal tract on bone mineral density
https://doi.org/10.31146/1682-8658-ecg-164-4-33-39
Abstract
Objective. Analyze the relationship between the surgical treatment of the upper gastrointestinal tract (GIT) and the decrease in bone mineral density (BMD) by comparison with reference age data and the control group. Methods. The medical data of 20 patients were analyzed with various types of surgical interventions on the upper GI tract (main group): 8 patients underwent various types of pancreatoduodenal resections, 11 - stomach resections, including two according to Billroth II, one patient underwent antral stenting. The patients’ age ranged from 53 to 84 years old, the median one being 70 years old, 13 men and 7 women. Measurements of lumbar spine BMD by the method of asynchronous CT densitometry were carried out using native images of the abdominal cavity, without contrast enhancement. The control group consisted of 35 patients who underwent an abdominal scan, without cancer pathology and without indications of a decrease in BMD. The age in the control group ranged from 43 to 86 years old, the median one being 65 years old, 22 men and 13 women. A multifactorial regression model was built to analyze the influencing factors on BMD. Results. A statistically significant dependence of the IPC on three factors was revealed: sex (p = 0.015), age (p = 0.001), and the presence of surgery. It was shown that among the main group of patients, the value of BMD was lower on average by 12.3 mg/ml as compared with the control group (p = 0.027), this corresponds to a decrease Zscore -0,35 SD. Conclusion. A statistically significant decrease BMD in patients after surgical treatment of the upper GIT, relative to the control group. It can be assumed that the emerging malabsorption syndrome is one of the prerequisites for the development of osteoporosis or osteopenia. Asynchronous CT densitometry is an effective method for monitoring bone mineral density, which provides additional information regarding BMD in patients under examination.
About the Authors
A. V. Petraikin
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies, Department of Healthcare of Moscow
Russian Federation
Russian Federation
A. V. Soloviev
Federal State Autonomous Educational Institution of Higher Education “I. M. Sechenov First Moscow State Medical University” of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation
Russian Federation
A. O. Chesnokova
Federal State Autonomous Educational Institution of Higher Education “I. M. Sechenov First Moscow State Medical University” of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation
Russian Federation
F. A. Petryaykin
Lomonosov Moscow State University, Faculty of Fundamental Medicine
Russian Federation
Russian Federation
L. A. Nisovtsova
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies, Department of Healthcare of Moscow
Russian Federation
Russian Federation
K. A. Sergunova
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies, Department of Healthcare of Moscow
Russian Federation
Russian Federation
E. S. Akhmad
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies, Department of Healthcare of Moscow
Russian Federation
Russian Federation
D. S. Semenov
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies, Department of Healthcare of Moscow
Russian Federation
Russian Federation
A. V. Vladzymyrskyy
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies, Department of Healthcare of Moscow
Russian Federation
Russian Federation
S. P. Morozov
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies, Department of Healthcare of Moscow
Russian Federation
Russian Federation
Review
For citations:
Petraikin A.V., Soloviev A.V., Chesnokova A.O., Petryaykin F.A., Nisovtsova L.A., Sergunova K.A., Akhmad E.S., Semenov D.S., Vladzymyrskyy A.V., Morozov S.P. Asynchronous quantitative computed tomography (QCT) in assessing the impact of the upper gastrointestinal tract on bone mineral density. Experimental and Clinical Gastroenterology. 2019;(4):33-39. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-164-4-33-39
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