Possible autofluorescent diagnostics of epithelial structures in the colon

Abstract

Objective: to determine the dependence of autofluorescent staining of epithelial colon lesions, depending on the histomorphological structure. Material and Methods: Video colonoscopy using autofluorescence was performed in 1674 patients. The patients’ age was 58±13.9, men were 761 (45.5%), women 913 (54.5%). Epithelial lesions were detected in 269 patients (16%). Endoscopic examinations were carried out according to a standard procedure using Olympus video colonoscopes, GF-260. Results: It was established that the presence of AF staining in the purple color of the epithelial colon lesions, as a marker of dysplasia, can serve as an additional criterion in the complex indications for their endoscopic removal. Conclusion: The developed method of using autofluorescent endoscopy is simple to perform and allows obtaining data that have a differential value on the presence of dysplastic changes in the epithelial colon lesions.