New options in management of Iron-Deficiency syndromes in Inflammatory Bowel Disease

The article describes the most common iron deficiency syndromes (IDS) in inflammatory bowel disease (IBD) and presents the modern principles of differential diagnosis of gastrointestinal disease, the advantages and disadvantages of standard methods for the correction of Iron-Deficiency (ID) and anemia in this group of patients. The authors give a circumstantial outline of their own data of examination and treatment of 77 patients with IBD and anemia, and prove the necessity of compulsory ferritin serum (FS) testing as the most important differential marker of the IDs., Inadequate production of erythropoietin as the main cause of anemia has been proven in 15% of patients with high FS values. On the contrary, the necessity of mandatory use of iron preparations in management of anemia was determined in 85% of patients. The high efficiency and safety of sucrosomial iron are proven in patients with IBD and anemia. The effectiveness of this method shows the normalization of hemoglobin in 68% of patients within 3 months. In contrast, intravenous iron administered during the inpatient treatment period is not sufficiently effective in this category of patients, which requires the continuation of outpatient therapy with preparations of sucrosomial iron. Conclusions: Based on the obtained data and international experience, there was formulated and substantiated the algorithm of differentiated therapy of IDS in patients with a mild form of IBD.

дефицит железа, железодефицитный синдром, воспалительные заболевания кишечника, лечение анемии, сукросомальное железо, внутривенное железо, iron deficiency syndrome, inflammatory bowel disease, treatment of anemia, sucrosomial iron, intravenous iron