Preview

Experimental and Clinical Gastroenterology

Advanced search

Systematic analysis of lactitol studies

https://doi.org/10.31146/1682-8658-ecg-162-2-131-142

Abstract

Lactitol is a prebiotic disaccharide that supports the functioning of lacto- and bifidobacteria, also inhibits the growth of pathogenic flora. The results of transcriptome and proteomic studies have shown that lactitol is characterized by unique absorption and processing mechanisms in lactobacteriathat distinguish it from other prebiotics. In high doses (5 … 50 g/day) lactiol is used as an osmotic laxative. Lactictol enhances the detoxification of the body (in particular, the excretion of ammonia and toxic amines). The detoxification effect of lactitol, lack of lactitol’seffect on blood lipid and glycemic profiles, lack of food intolerance and rare occurrenceof side effects (flatulence, transient diarrhea when the dose is exceeded) make lactitol an important tool in the treatment of dysbiosis, liver disease and hepatic encephalopathy.

About the Authors

O. A. Gromova
Big Data Storage and Analysis Center (CCHD), Moscow State University
Russian Federation


I. Yu. Torshin
Big Data Storage and Analysis Center (CCHD), Moscow State University
Russian Federation


V. A. Maximov
Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuous Professional Education” of the Ministry of Healthcare of the Russian Federation
Russian Federation


A. N. Gromov
Big Data Storage and Analysis Center (CCHD), Moscow State University
Russian Federation


K. V. Rudakov
Big Data Storage and Analysis Center (CCHD), Moscow State University
Russian Federation


Review

For citations:


Gromova O.A., Torshin I.Yu., Maximov V.A., Gromov A.N., Rudakov K.V. Systematic analysis of lactitol studies. Experimental and Clinical Gastroenterology. 2019;(2):131-142. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-162-2-131-142

Views: 561


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1682-8658 (Print)