Biomarkers of the inflammatory bowel diseases
https://doi.org/10.31146/1682-8658-ecg-157-9-4-9
Abstract
The prevalence of inflammatory bowel disease (IBD) (ulcerative colitis (UC) and Crohn's disease (CD)) increases annually. The problems of early and non-invasive diagnosis of IBD remain relevant. The purpose of this review is to analyze the diagnostic value of various biological markers of IBD. The main objective of the search for new biomarkers of IBD is to minimize the possibility of repeated endoscopic studies for early diagnosis and determination of disease activity, evaluation of the effectiveness of treatment and prevention of complications. Widely used, routine, and also perspective biological markers allowing to verify the diagnosis of IBD, to estimate a course and a prognosis of a disease are presented.
Keywords
М2-пируваткина,
матриксные металлопротеиназы (ММП),
кальпротектин,
лактоферрин,
антинейтрофильные цитоплазматические антитела (ANCA),
анти-Saccharomyces cerevisae антитела (ASCA),
M2-pyruvate kinase,
matrix metalloproteinases (MMP),
calprotectin,
lactoferrin,
antineutrophil cytoplasmic antibodies (ANCA),
anti-Saccharomyces cerevisae antibodies ASCA
About the Authors
I. V. Kozlova
Saratov State Medical University named after V. I. Razumovsky
Russian Federation
Russian Federation
M. M. Kudishina
Saratov State Medical University named after V. I. Razumovsky
Russian Federation
Russian Federation
A. L. Pahomova
Saratov State Medical University named after V. I. Razumovsky
Russian Federation
Russian Federation
Review
For citations:
Kozlova I.V., Kudishina M.M., Pahomova A.L. Biomarkers of the inflammatory bowel diseases. Experimental and Clinical Gastroenterology. 2018;(9):4-9. (In Russ.) https://doi.org/10.31146/1682-8658-ecg-157-9-4-9
Views:
376
Email this article 