Liver - Is The Target Organ Of The Hormone Therapy In Women

Abstract

The article presents data of the efficiency of exogenous sex hormones use in the maintenance of women’s health, their classification, and also the mechanism of action of exogenous estrogens and gestagens from the point of view of “first passage through the liver” was studied in detail. Understanding the importance of hormone therapy for women, a great attention is paid to the problem of ensuring its safety, specifically, of the target organ - the liver. The risk factors of hepatotoxicity of exogenous sex hormones are discussed in details, the tactic of early diagnosis, treatment and prevention of liver damage on the background of hormone therapy with estrogenic and gestational drugs is defined.