Lactotrophy of infants in terms of digestiology (Assembly speech)

Abstract

The relevance of milk-feeding of babies, the importance of not only the composition and properties of breast milk, but also the technology of enzymatic degradation of its nutrients are cosidered In the Assembly speech. First, it is produced according to the type of its own digestion by hydrolases of the digestive glands and the small intestine of the infant, the complex of which is formed antenatally and called the starting multienzyme digestive potential in the newborn child. Its quantitative characterization is possible by determining the main digestive hydrolases in the amniotic fluid, in the blood of the umbilical cord and in the gastric aspirate of the infant. The expression of this potential in the point system is proposed. With incomplete gestation, the digestive potential is reduced. Secondly, hydrolysis of breast milk nutrients is carried out by its own hydrolases in the autolytic type of digestion. The dynamics of secretion of hydrolases by the mammary glands of healthy women during one year of lactation was studied. The quantitative dependence of the hydrolase secretion on its value in the first lactation month is described with a general tendency to a decrease in the hydrolase content in milk with an increase in the monthly lactation period, and the dependence of the secretion of enzymes by the mammary glands from the age of the pregnant women. The dynamic convergence of the multienzyme digestive potentials of the child's digestion system and the mother's milk it takes is relevant in lactotrophy. Based on the results of peptidic analysis of auto-and inragastral proteolysis of breast milk, milk hydrolases are not only considered as trophotropic participants in the degradation of its nutrients, but also in formation of by milk proteases functionally multipotent regulatory peptides with a characteristic change in their number and content in the dynamics of infant feeding and timing of gestation.