NONCELIAC SENSITIVITY TO GLUTEN
Abstract
Nonceliac sensitivity to gluten (NCSG) is a new syndrome manifested by a gluten intolerance is not allergic and non-autoimmune condition in which eating gluten can cause symptoms similar to the manifestations of celiac disease. NCSG the diagnosis requires the exclusion of coeliac disease and allergies to wheat. NCSG occurs mainly by intestinal symptoms that appear soon after eating gluten-containing foods and are rapidly after discontinuation of gluten. NCSG is not accompanied by retardation in physical and sexual development, weight loss and autoimmune or allergic comorbidity. The basis for the development of this syndrome probably is the effect of microbiota and metabolites of gluten on the neuroreceptors, as well as a mild inflammation of the intestinal mucosa without atrophy. NCSG more characteristic of adults than children and often manifests at a young age. The article presents the differential diagnostic signs of NCSG, celiac disease and allergies to wheat.
About the Author
E. A. Kornienko
Saint-Petersburg state pediatric medical University
Russian Federation
Russian Federation
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Review
For citations:
Kornienko E.A. NONCELIAC SENSITIVITY TO GLUTEN. Experimental and Clinical Gastroenterology. 2017;(3):89-98. (In Russ.)
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