PECULIARITIES OF MICROFLORA OF THE COLONIC BIOTOPE COLONIZED BY S. AUREUS AND C. ALBICANS
Abstract
Intestinal microflora is considered as the main determinant of human health and disease. There is evidence that changes in the relationship between the composition of intestinal microbiota and the human body can be accompanied by the development of allergic and immunopathological conditions, as well as a number of diseases. The aim of the investigation was to assess changes in the lumen of the microbial composition of the large intestine in the case of isolation of S. aureus and C. albicans. Results. In the case of the presence of S. aureus a decrease in the frequency of isolation of typical variants of E. coli. This activity of S. aureus is suppressed by Candida, when the occurrence of E. coli corresponds to the level of the control group. In the presence of C. albicans alone, there is a slight decrease in the allocation of typical E. coli variants. Conclusion. The presence of C. albicans eliminates S. aureus antagonistic relationship with E. coli. On the other hand, the presence of S. aureus and C. albicans both individually and jointly contribute to the development of atypical variants of E. coli. Thus, the studies have shown that the detection of S. aureus and/or C. albicans in the large cell biotope can significantly change the composition of the microbiota, which may affect the functional activity of the colon mucosa and the whole human body.
About the Authors
A. P. Godovalov
Acad. E. A. Wagner Perm State Medical University
Russian Federation
Russian Federation
A. A. Antonyan
Acad. E. A. Wagner Perm State Medical University
Russian Federation
Russian Federation
E. A. Gorbunova
Acad. E. A. Wagner Perm State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Godovalov A.P., Antonyan A.A., Gorbunova E.A. PECULIARITIES OF MICROFLORA OF THE COLONIC BIOTOPE COLONIZED BY S. AUREUS AND C. ALBICANS. Experimental and Clinical Gastroenterology. 2018;(5):61-65. (In Russ.)
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