PANCREATIC CANCER RISK FACTORS: A SUMMARY REVIEW OF META-ANALYTICAL AND PROSPECTIVE COHORT STUDIES PART 1. COFFEE AND TEA CONSUMPTION
Abstract
Pancreatic cancer (PC) is one of the top 5 causes of mortality from cancer. The role of dietary factors in the etiology of PC is unclear. We reviewed some meta-analytical or pooled reports dealing with the association between coffee (C) and tea (T) consumption and PC risk. C components can have anticarcinogenic effect: meta-analysis by Dong (2011) confirmed, that pooled relative risk (RR) of PC in high C lovers comparing with non/lowest C drinkers was 0.68 (95% CI 0.51-0.84). But in the “US NIH-AARP Diet and Health Study” (2015) after adjustment for smoking, PC risk were not significant: never C drinkers compared with C drinkers≥6 cups per day (cpd) HR1.24 (0.93-1.65). In the European Prospective Investigation (2013) neither C, nor T were also associated with PC risk, but the previous Italian multicenter study (1995) was demonstrated, that ingestion of >3 cpd lead to significantly increased PC risk (odds ratio (OR) 2.53; 1.53-4.18). A meta-analysis by Zeng (2014) indicate, that green T consumption >2 cpd (OR0.95, 0.85-1.06) was not associated with PC risk. However, the subgroup analysis of different countries in meta-analysis by Chen (2014) showed a statistical decrease in PC risk by high T consumption in a Chinese population (Risk ratio=0.76, 0.59-0.98). Nevertheless meta-analysis, pooled and case-control studies are prone to some limitations (recall, selection bias) - different dietary patterns, adjustment for different confounders, etc. Further research is needed to clarify the biological mechanisms in the possible inverse relationship between C, T intake and PC risk.
About the Author
I. N. Grigorieva
Research Institutе of Internal and Preventive Medicine - Branch of Federal State Budget Scientefic Institution The Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences; National Research State University
Russian Federation
Russian Federation
References
1. Ferlay J., Soerjomataram I., Ervik M., et al. GLOBOCAN2012 v1.1, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet] Lyon, France: International Agency for Research on Cancer; 2014.
2. Michaud D. S. Role of bacterial infections in pancreatic cancer. //Carcinogenesis. 2013; 34(10): 2193-2197.
3. Jemal A., Bray F., Center M., et al. Global cancer statistics. // Cancer J. Clin. 2011;61:69-90.
4. Dong J., Zou J., Yu X. Coffee drinking and pancreatic cancer risk: a meta-analysis of cohort studies. //World J. Gastroenterol. 2011;17(9):1204-1210.
5. Bode A. M., Dong Z. The enigmatic effects of caffeine in cell cycle and cancer. //Cancer Lett. 2007; 247(1):26-39.
6. Guertin K. A., Freedman N. D., Loftfield E., et al. A prospective study of coffee intake and pancreatic cancer: results from the NIH-AARP Diet and Health Study. //Br. J. Cancer. 2015;113(7):1081-1085.
7. Bhoo-Pathy N., Uiterwaal C. S., Dik V. K., et al. Intake of coffee, decaffeinated coffee, or tea does not affect risk for pancreatic cancer: results from the European Prospective Investigation into Nutrition and Cancer Study. //Clin. Gastroenterol. Hepatol. 2013;11(11):1486-1492.
8. Bidel S., Hu G., Jousilahti P., et al. Coffee consumption and risk of gastric and pancreatic cancer - a prospective cohort study. //Int. J. Cancer. 2013;132(7): 1651-1659.
9. Turati F., Galeone C., Edefonti V., et al. A meta-analysis of coffee consumption and pancreatic cancer. //Ann Oncol. 2012;23(2):311-318.
10. Gullo L., Pezzilli R., Morselli-Labate A.M., et al. Coffee and cancer of the pancreas: an Italian multicenter study. // Pancreas. 1995;11(3):223-229.
11. Nie K., Xing Z, Huang W, et al. Coffee intake and risk of pancreatic cancer: an updated meta-analysis of prospective studies. //Minerva Med. 2016;107(4): 270-278.
12. Ran H. Q., Wang J. Z., Sun C. Q. Coffee Consumption and Pancreatic Cancer Risk: An Update Meta-analysis of Cohort Studies. //Pak J. Med. Sci. 2016;32(1): 253-259.
13. Nishi M., Ohba S., Hirata K. et al. Dose-response relationship between coffee and the risk of pancreas cancer. // Jpn. J. Clin. Oncol. 1996;26(1):42-48.
14. Wang A., Wang S., Zhu C., et al. Coffee and cancer risk: A meta-analysis of prospective observational studies. //Sci. Rep. 2016; 6, 33711.
15. Feng R., Lu Y., Bowman L. L., et al. Inhibition of activator protein-1, NF-kappaB, and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acid. // J. Biol. Chem. 2005; 280(30):27888-27895.
16. Dong S., Kong J., Kong J., et al. Low Concentration of Caffeine Inhibits the Progression of the Hepatocellular Carcinoma via Akt Signaling Pathway. //Anticancer Agents Med. Chem. 2015; 15(4):484-492.
17. Higdon J. V., Frei B. Coffee and health: a review of recent human research. //Crit. Rev. Food Sci. Nutr. 2006; 46(2):101-23.
18. Li D., Jiao L. Molecular epidemiology of pancreatic cancer. //Int. J. Gastrointest. Cancer. 2003;33(1):3-14.
19. Porta M., Malats N., Guarner L., et al. Association between coffee drinking and K-ras mutations in exocrine pancreatic cancer. PANKRAS II Study Group. // J. Epidemiol. Community Health. 1999; 53(11): 702-709.
20. Genkinger J. M., Li R., Spiegelman D., et al. Coffee, tea, and sugar-sweetened carbonated soft drink intake and pancreatic cancer risk: a pooled analysis of 14 cohort studies. //Cancer Epidemiol. Biomarkers Prev. 2012;21(2):305-318.
21. Appari M., Babu K. R., Kaczorowski A. et al. Sulforaphane, quercetin and catechins complement each other in elimination of advanced pancreatic cancer by miR-let-7 induction and K-ras inhibition. //Int. J. Oncol. 2014;45(4):1391-400.
22. Zhang Y. F., Xu Q., Lu J., et al. Tea consumption and the incidence of cancer: a systematic review and meta-analysis of prospective observational studies. //Eur. J. Cancer Prev. 2015;24(4):353-362.
23. Zeng J. L., Li Z. H., Wang Z. C., Zhang H. L. Green tea consumption and risk of pancreatic cancer: a meta-analysis. // Nutrients. 2014;6(11):4640-4650.
24. Chang B., Sang L., Wang Y., et al. Consumption of tea and risk for pancreatic cancer: a meta-analysis of published epidemiological studies. //Nutr. Cancer. 2014;66(7):1109-1123.
25. Chen K., Zhang Q., Peng M., et al. Relationship between tea consumption and pancreatic cancer risk: a meta-analysis based on prospective cohort studies and case-control studies. // Eur. J. Cancer Prev. 2014;23(5):353-360.
26. Shibata A., Mack T. M., Paganini-Hill A., et al. A prospective study of pancreatic cancer in the elderly. // Int. J. Cancer. 1994;58:46-49.
27. Zatonski W., Boyle P., Przewozniak K., Maisonneuve P. Cigarette smoking, alcohol, tea and coffee consumption and pancreas cancer risk: a case-control study from Opole, Poland. //Int. J. Cancer. 1993;53:601-607.
28. Jansen R. J., Tan X-L., Petersen G. M. Gene-by-Environment Interactions in Pancreatic Cancer: Implications for Prevention. //Yale J. Biol. Med. 2015; 88(2): 115-126.
29. Bracken M. B., Triche E., Grosso L., et al. Heterogeneity in assessing self-reports of caffeine exposure: implications for studies of health effects. //Epidemiology. 2002; 13(2):165-171.
Review
For citations:
Grigorieva I.N. PANCREATIC CANCER RISK FACTORS: A SUMMARY REVIEW OF META-ANALYTICAL AND PROSPECTIVE COHORT STUDIES PART 1. COFFEE AND TEA CONSUMPTION. Experimental and Clinical Gastroenterology. 2018;(3):93-96. (In Russ.)
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