SYSTEMTIZING CLASSIFICATION OF MULTIFOCAL LESIONS OF THE MUCOSA OF THE DIGESTIVE TRACT BY NON-STEROIDAL ANTI-INFLAMMATORY AND ANTITROMBOTIC DRUGS (“MOSCOW CLASSIFICATION”)

In order to develop an algorithm for managing patients receiving NSAIDs and anti-thrombotic therapy, as well as classification of lesions of the mucosa of the digestive tract, against the background of the treatment, we used the experience of foreign colleagues and information resources: PubMed, Cochrane Library, MDConsult, DynaMed, Google Scholar, TRIP Database, which today is the most comprehensive in terms of coverage by the public meta-search system, which has an advanced document sorting system, existing normative documents, as well as own experience. The algorythm for management of patients cured with NSAIDs or АТА included assessment of the patient’s condition before the start of treatment, dynamic monitoring of complications based on clinical and laboratory data, endoscopic diagnostic data, and a decision support system in the form of the “Russian classification” of esophagogastroduodenoenterocolatopathy. The developed “Moscow classification” of multifocal lesions of the mucosa of the digestive tract with nonsteroidal anti-inflammatory and antithrombotic agents is presented in the form of a cascade that includes a common scale, an expanded (specifying) scale, and a stratification of the risks of recurrence of bleeding and thromboembolic complications. Тhe proposed “Moscow classification” of lesions of the mucosa of the digestive tract with non-steroidal anti-inflammatory drugs and drugs for lowering blood clotting (L. B. Lazebnik, G. V. Belova) is a testament to the medicine of “Three P” - personified, preventive and predictive, accounting for a significant number of gender, anamnesis, functional and clinical-laboratory indicators. The application of the Russian classification refers to the decision-support system for the tactics of conducting an extremely complex category of patients with severe comorbid pathology.

«Московская классификация», comorbid pathology, non-steroidal anti-inflammatory drugs, antithrombotic drugs, “Moscow classification”, risk of bleeding recurrence, risk of thromboembolic complications, multifocal lesions of the mucosa of the digestive tract

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