PREVENTION OF NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH CHOLELITHIASIS AFTER CHOLECYSTECTOMY

Abstract

We examined 60 patients aged 38 ± 10.3 years who underwent cholecystectomy for cholelithiasis. According to ultrasonography, all patients did not have signs of non-alcoholic fatty liver disease. The observation period was 1 year. The patients were divided into 2 groups of 30 people each. Group 1 included patients assigned to: Ursofalk, Mukofalk and Hofitol. Group 2 included patients who received symptomatic therapy. All patients were examined: a biochemical blood test and ultrasonography of the abdominal organs, before surgery and 6 and 12 months after cholecystectomy. Of the 60 patients enrolled in the study, 21.6% by the end of the first year after cholecystectomy, ultrasonography from the liver showed signs of non-alcoholic fatty liver disease. In the first group of patients, by the end of the first year after cholecystectomy, signs of non-alcoholic fatty liver disease were found to be 6.6%. In the second group, the signs of non-alcoholic fatty liver disease appeared in 36.6% of patients. Against the backdrop of using the prophylaxis scheme developed by Ursofalk, Mukofalk and Hofitol, the incidence of non-alcoholic fatty liver disease in patients with cholelithiasis is lower by the end of the first year after cholecystectomy than in patients who did not use this scheme 6-fold.