DIFFUSE FAMILY POLYPOSIS IN CHILDREN
Abstract
It was performed the analysis of modern ideas about the features of etiopathogenesis, diagnosis and treatment of diffuse family polyposis. Diffuse family polyposis or familial adenomatous polyposis (FAP) refers to genetically conditioned multi-tumor syndromes, which represent a separate group of diseases characterized by polyps in the gastrointestinal tract and are considered as potentially malignant multifocal process. The most frequent clinical manifestations of pathology and methods of its diagnostics are described, features of monitoring of this category of patients are characterized. The methods of treatment of FAP are considered, while all the revealed colloctal polyps should be removed. The method of choice in this case is endoscopic polypectomy, with their location no more than 5-7 cm from the edge of the anus - transansal resection. The need for early diagnosis and treatment of this category of patients is indicated, while specialists should be informed about extraintestinal benign and malignant manifestations of FAP and associations between them. It was noted that a timely diagnosis of hereditary syndrome in patients with high-risk FAP, as well as dynamic monitoring of them, helps to recognize the presence of a malignant tumor and provides the possibility of sparing treatment in the early stages of the disease.
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For citations:
Sichinava I.V. DIFFUSE FAMILY POLYPOSIS IN CHILDREN. Experimental and Clinical Gastroenterology. 2018;(1):61-67. (In Russ.)
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