NEW POSSIBILITY OF USE OF BACTERIOPHAGES IN THE COMPLEX THERAPY OF RATANASOPHA DISEASES IN CHILDREN

Abstract

To evaluate the effectiveness of inhalation phagotherapy in diseases of the oropharynx in children. Patients and methods. 120 patients from 4 to 17 years, including 60 children with acute bilateral upper-jaw sinusitis, 30 people with acute hemisinusitis and pansinusitis, respectively. The efficiency of bacteriophages was assessed by three main criteria: 1. anoscopically picture with the use of endoscopic techniques with videoarchive; 2. data of bacteriological research; 3. X-ray computed tomography (CT) before treatment and after the therapy. Inhalation therapy was carried out using compressor nebulizers OMRON and PARISINUS. At admission of the patient, on the 5th and 10th days of the carried-out phagotherapy results of bacteriological research testify to lysis of the causative agent of the disease by the 10th days in 98 % of crops at all 120 patients of the investigated groups. CT data before and after treatment confirmed the positive dynamics and resolution of the process in 84 %. Phagotherapy in gastroenterology and otorhinolaryngology, especially in childhood, is a full-fledged method in complex therapy, allows optimizing the entire process of treating patients, in many cases copes with the problem of antibiotic resistance, prevents the development of early and late postoperative complications in many areas of surgical treatment of the pathology of the oropharynx.