GENOTYPE Helicobacter Pylori AT NSAIDS TAKING PATIENTS
Abstract
The study included 34 patients (15 men and 19 women, average age 56,7±1,46). The test was divided into three groups, with the additional inclusion criterion of I and II groups was the use of a patient NSAIDs for at least 30 calendar days prior to the survey. A study of strains of Helicobacter pylori (HP) in gastric mucosa of adult patients receiving non-steroidal anti-inflammatory drugs (NSAIDs). HP genotyping was performed by PCR. In the General structure of the studied biopsy specimens was often identified genotype vac A s1/m1, cag A+; iceA1 (7 cases out of 34 (of 20.58 %), p<0.05). The distribution of genotypes in the clinical groups were quite heterogeneous, the Results of the conducted studies, despite some heterogeneity, indicate the presence of statistically significant differences depending on the presence of erosive-ulcerative changes and factors of NSAIDs.
About the Authors
N. V. Shirinskaya
Omsk State Medical Information-Analytical Centre
Russian Federation
Russian Federation
E. G. Pomorgaylo
Omsk State Medical University
Russian Federation
Russian Federation
V. A. Akhmedov
Omsk State Medical University
Russian Federation
Russian Federation
T. V. Vaskina
Omsk State Medical Diagnostic Center
Russian Federation
Russian Federation
N. P. Kirichenko
Omsk State Medical Diagnostic Center
Russian Federation
Russian Federation
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Review
For citations:
Shirinskaya N.V., Pomorgaylo E.G., Akhmedov V.A., Vaskina T.V., Kirichenko N.P. GENOTYPE Helicobacter Pylori AT NSAIDS TAKING PATIENTS. Experimental and Clinical Gastroenterology. 2017;(12):9-13. (In Russ.)
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